A guide to genome engineering with programmable nucleases
Programmable nucleases—including zinc-finger nucleases (ZFNs), transcription activator-
like effector nucleases (TALENs) and RNA-guided engineered nucleases (RGENs) derived …
like effector nucleases (TALENs) and RNA-guided engineered nucleases (RGENs) derived …
Vector biology meets disease control: using basic research to fight vector-borne diseases
WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
Genome engineering with targetable nucleases
D Carroll - Annual review of biochemistry, 2014 - annualreviews.org
Current technology enables the production of highly specific genome modifications with
excellent efficiency and specificity. Key to this capability are targetable DNA cleavage …
excellent efficiency and specificity. Key to this capability are targetable DNA cleavage …
Insecticide resistance and management strategies in urban ecosystems
The increased urbanization of a growing global population makes imperative the
development of sustainable integrated pest management (IPM) strategies for urban pest …
development of sustainable integrated pest management (IPM) strategies for urban pest …
Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti
The development of CRISPR/Cas9 technologies has dramatically increased the accessibility
and efficiency of genome editing in many organisms. In general, in vivo germline expression …
and efficiency of genome editing in many organisms. In general, in vivo germline expression …
Progress and prospects of CRISPR/Cas systems in insects and other arthropods
Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-
associated gene Cas9 represent an invaluable system for the precise editing of genes in …
associated gene Cas9 represent an invaluable system for the precise editing of genes in …
Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti
Conventional control strategies for mosquito-borne pathogens such as malaria and dengue
are now being complemented by the development of transgenic mosquito strains …
are now being complemented by the development of transgenic mosquito strains …
Delivery and therapeutic applications of gene editing technologies ZFNs, TALENs, and CRISPR/Cas9
JS LaFountaine, K Fathe, HDC Smyth - International journal of …, 2015 - Elsevier
In recent years, several new genome editing technologies have been developed. Of these
the zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …
the zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …
Gene drive for mosquito control: where did it come from and where are we headed?
Mosquito-borne pathogens place an enormous burden on human health. The existing toolkit
is insufficient to support ongoing vector-control efforts towards meeting disease elimination …
is insufficient to support ongoing vector-control efforts towards meeting disease elimination …
Generation of improved humanized mouse models for human infectious diseases
MA Brehm, MV Wiles, DL Greiner, LD Shultz - Journal of immunological …, 2014 - Elsevier
The study of human-specific infectious agents has been hindered by the lack of optimal
small animal models. More recently development of novel strains of immunodeficient mice …
small animal models. More recently development of novel strains of immunodeficient mice …