The concept of insulin resistance has been around since a few decades after the discovery
of insulin itself. To allude to the classic Charles Dicken's novel published 62 years before the …

Nutrient sensing and metabolic homeostasis play an important role in the proper growth and
development of an organism, and also in the energy intensive process of reproduction …

Insulin signaling plays a pivotal role in metabolic control and aging, and insulin accordingly
is a key factor in several human diseases. Despite this importance, the in vivo activity …

Insects have evolved a variety of neurohormones that enable them to maintain their nutrient
and osmotic homeo-stasis. While the identities and functions of various insect metabolic and …

Animals often grow and develop in unpredictable environments where factors like food
availability, temperature, and oxygen levels can fluctuate dramatically. To ensure proper …

A new study reveals that Drosophila insulin-like peptides (Dilps) accumulate in adipokinetic
hormone (AKH)-producing cells in a manner dependent on the insulin-binding protein …