OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Atherosclerosis develops due to lipid accumulation in the arterial wall and sclerosis as result
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …

Although immune checkpoint blockade has shown initial success for various cancers, only a
small subset of patients benefits from this therapy. Some chemotherapeutic drugs have been …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Abstract Families of innate immune receptors serve as the bodies primary defence system
by recognising and rapidly responding to infection by microorganisms or to endogenous …

OBJECTIVE We assessed the prevalence of and risk factors for diabetic peripheral
neuropathy (DPN) in youth with type 1 diabetes (T1D) and type 2 diabetes (T2D) enrolled in …

Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …

High-density lipoprotein (HDL) mediates reverse cholesterol transport and is known to be
protective against atherosclerosis. In addition, HDL has potent anti-inflammatory properties …

Recent studies have indicated that high-density lipoproteins (HDLs) and their major
structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are …

HDL cholesterol activates endothelial cell production of the atheroprotective signaling
molecule NO, and it promotes endothelial repair. In this issue of the JCI, Besler et al. provide …