Hyaluronan-based hydrogel integrating exosomes for traumatic brain injury repair by promoting angiogenesis and neurogenesis
X Liu, C Wu, Y Zhang, S Chen, J Ding, Z Chen… - Carbohydrate …, 2023 - Elsevier
With wide clinical demands, therapies for traumatic brain injury (TBI) are far from satisfactory.
Combining the merits of stem cells but avoiding the risk of immunologic rejection, bone …
Combining the merits of stem cells but avoiding the risk of immunologic rejection, bone …
[HTML][HTML] 3D bioprinted multilayered cerebrovascular conduits to study cancer extravasation mechanism related with vascular geometry
Cerebral vessels are composed of highly complex structures that facilitate blood perfusion
necessary for meeting the high energy demands of the brain. Their geometrical complexities …
necessary for meeting the high energy demands of the brain. Their geometrical complexities …
[HTML][HTML] Three-dimensional bioprinting of artificial blood vessel: Process, bioinks, and challenges
YC Hou, X Cui, Z Qin, C Su, G Zhang… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
The coronary artery bypass grafting is a main treatment for restoring the blood supply to the
ischemic site by bypassing the narrow part, thereby improving the heart function of the …
ischemic site by bypassing the narrow part, thereby improving the heart function of the …
Exploring the properties and potential of the neural extracellular matrix for next‐generation regenerative therapies
JA Ortega, GP Soares de Aguiar… - Wiley …, 2024 - Wiley Online Library
The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …
Bioactive self-healing hydrogel based on tannic acid modified gold nano-crosslinker as an injectable brain implant for treating Parkinson's disease
J Xu, TY Chen, CH Tai, S Hsu - Biomaterials Research, 2023 - spj.science.org
Background Parkinson's disease (PD) is one of the most common long-term
neurodegenerative diseases. Current treatments for PD are mostly based on surgery and …
neurodegenerative diseases. Current treatments for PD are mostly based on surgery and …
[HTML][HTML] Hypoxia-pretreated mesenchymal stem cell-derived exosomes-loaded low-temperature extrusion 3D-printed implants for neural regeneration after traumatic …
X Liu, J Wang, P Wang, L Zhong, S Wang… - … in bioengineering and …, 2022 - frontiersin.org
Regenerating brain defects after traumatic brain injury (TBI) still remains a significant
difficulty, which has motivated interest in 3D printing to design superior replacements for …
difficulty, which has motivated interest in 3D printing to design superior replacements for …
A generic pump‐free organ‐on‐a‐chip platform for assessment of intestinal drug absorption
Organ‐on‐a‐chip technology has shown great potential in disease modeling and drug
evaluation. However, traditional organ‐on‐a‐chip devices are mostly pump‐dependent with …
evaluation. However, traditional organ‐on‐a‐chip devices are mostly pump‐dependent with …
3D chitosan scaffolds support expansion of human neural stem cells in chemically defined condition
FC Chang, MM James, AM Qassab, Y Zhou, Y Ando… - Matter, 2023 - cell.com
The use of human neural stem cells (hNSCs) for clinical cell therapies is limited by the lack
of effective culture substrates to produce hNSCs. Animal-sourced substrates could result in …
of effective culture substrates to produce hNSCs. Animal-sourced substrates could result in …
Decellularized extracellular matrix and mesenchymal stem cells promote recovery in traumatic brain injury by synergistically enhancing neurogenesis and attenuating …
X Zhang, B Wang, H Hong, Y Wang, J Liu, C Liu… - Journal of Materials …, 2023 - Elsevier
Damaged neurons and harsh microenvironments contribute to the injury cascades following
traumatic brain injury (TBI). Mesenchymal stem cell (MSC) therapy is considered a viable …
traumatic brain injury (TBI). Mesenchymal stem cell (MSC) therapy is considered a viable …
Stem cells in central nervous system diseases: Promising therapeutic strategies
C Ying, J Zhang, H Zhang, S Gao, X Guo, J Lin… - Experimental …, 2023 - Elsevier
Central nervous system (CNS) diseases are a leading cause of death and disability. Due to
CNS neurons have no self-renewal and regenerative ability as they mature, their loss after …
CNS neurons have no self-renewal and regenerative ability as they mature, their loss after …