PSMA-targeted radiopharmaceuticals for imaging and therapy

HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

Preclinical and clinical status of PSMA-targeted alpha therapy for metastatic castration-resistant prostate cancer

A Juzeniene, VY Stenberg, ØS Bruland, RH Larsen - Cancers, 2021 - mdpi.com
Simple Summary Currently, there is no treatment that can cure patients with late stage
metastatic prostate cancer. Prostate-specific membrane antigen is a type of protein …

Predictors of overall and disease-free survival in metastatic castration-resistant prostate cancer patients receiving 225Ac-PSMA-617 radioligand therapy

M Sathekge, F Bruchertseifer, M Vorster… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Metastatic prostate carcinoma overexpresses prostate-specific membrane antigen (PSMA),
making this antigen a suitable target for radioligand therapy of the disease. Here we report …

The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research

EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …

Review of therapeutic applications of radiolabeled functional nanomaterials

J Jeon - International journal of molecular sciences, 2019 - mdpi.com
In the last two decades, various nanomaterials have attracted increasing attention in medical
science owing to their unique physical and chemical characteristics. Incorporating …

PSMA-targeting radiopharmaceuticals for prostate cancer therapy: recent developments and future perspectives

M El Fakiri, NM Geis, N Ayada, M Eder, AC Eder - Cancers, 2021 - mdpi.com
Simple Summary One of the most frequently diagnosed cancer in men is adenocarcinoma of
the prostate. Once the disease is metastatic, only very limited treatment options are …

PET/CT for evaluation of ovarian cancer

J Kemppainen, J Hynninen, J Virtanen… - Seminars in nuclear …, 2019 - Elsevier
Ovarian cancer is the leading cause of death from gynecologic cancer in the developed
countries. It is usually diagnosed in advanced stage since it is often symptomless or …

Radiolabelled peptides for positron emission tomography and endoradiotherapy in oncology

C Rangger, R Haubner - Pharmaceuticals, 2020 - mdpi.com
This review deals with the development of peptide-based radiopharmaceuticals for the use
with positron emission tomography and peptide receptor radiotherapy. It discusses the pros …

Preparation of the alpha‐emitting prostate‐specific membrane antigen targeted radioligand [212Pb]Pb‐NG001 for prostate cancer

VY Stenberg, A Juzeniene, Q Chen… - Journal of Labelled …, 2020 - Wiley Online Library
Prostate‐specific membrane antigen (PSMA) is the most promising target for radioligand
therapy of prostate cancer. The aim of this study was to prepare a small molecular ligand p …

CD38‐Targeted Theranostics of Lymphoma with 89Zr/177Lu‐Labeled Daratumumab

L Kang, C Li, ZT Rosenkrans, N Huo, Z Chen… - Advanced …, 2021 - Wiley Online Library
Lymphoma is a heterogeneous disease with varying clinical manifestations and outcomes.
Many subtypes of lymphoma, such as Burkitt′ s lymphoma and diffuse large B cell …