Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic
potential in pathological anxiety. Dosing guidelines to inform future human studies are …

The endocannabinoid system (ECS) regulates brain development and function, energy
metabolism and stress in a sex-, age-and tissue-dependent manner. The ECS comprises …

Postpartum depression (PPD) is a severe psychiatric disorder with devastating
consequences on child development and mother's health. Dysregulation of glutamatergic …

Increasing evidence suggests that the neurobiological processes that govern learning and
memory can be different in males and females, but many of the specific mechanisms …

Gender is considered as a pivotal determinant of mental health. Indeed, several psychiatric
disorders such as anxiety and depression are more common and persistent in women than …

Oleanolic acid (OA) and ursolic acid (UA) are structural isomeric triterpenoids. Both
triterpenoids have been reported to be able to improve depression. However, no studies …

Exposure to stressors in early postnatal life induces long-lasting modifications in brain
function. This plasticity, an essential characteristic of the brain that enables adaptation to the …

Addiction is a worldwide problem that has a negative impact on society by imposing
significant costs on health care, public security, and the deactivation of the community …

Early adversity, the loss of the inhibitory GABAergic interneuron parvalbumin, and elevated
neuroinflammation are associated with depression. Individuals with a maltreatment history …

Recent research has highlighted cerebellar involvement in cognition and several psychiatric
conditions such as mood and anxiety disorders and schizophrenia. Attention …