Advancements and challenges in antifungal therapeutic development
Over recent decades, the global burden of fungal disease has expanded dramatically. It is
estimated that fungal disease kills approximately 1.5 million individuals annually; however …
estimated that fungal disease kills approximately 1.5 million individuals annually; however …
Immunocompromised host section: Adoptive T-cell therapy for dsDNA viruses in allogeneic hematopoietic cell transplant recipients
CS Walti, C Stuehler, D Palianina… - Current Opinion in …, 2022 - journals.lww.com
Immunocompromised host section: Adoptive T-cell therapy for... : Current Opinion in
Infectious Diseases Immunocompromised host section: Adoptive T-cell therapy for dsDNA …
Infectious Diseases Immunocompromised host section: Adoptive T-cell therapy for dsDNA …
Final outcomes from a phase 2 trial of posoleucel in allogeneic hematopoietic cell transplant recipients
SS Dadwal, R Bansal, MW Schuster, JA Yared… - Blood …, 2024 - ashpublications.org
Allogeneic hematopoietic cell transplantation (allo-HCT) recipients are susceptible to viral
infections. We conducted a phase 2 trial evaluating the safety and rate of clinically significant …
infections. We conducted a phase 2 trial evaluating the safety and rate of clinically significant …
Adoptive immunotherapy for prophylaxis and treatment of cytomegalovirus infection
CP Ouellette - Viruses, 2022 - mdpi.com
Cytomegalovirus (CMV), a member of the Herpesviridae family, is frequent among
hematopoietic cell transplant (HCT) and solid organ transplant (SOT) recipients in absence …
hematopoietic cell transplant (HCT) and solid organ transplant (SOT) recipients in absence …
Epstein–Barr virus posttransplant lymphoproliferative disorder: update on management and outcomes
With an increasing number of risk groups for developing EBV PTLD in HCT and SOT,
management strategies using prophylaxis or preemptive therapy remain standard of care …
management strategies using prophylaxis or preemptive therapy remain standard of care …
T cell responses to control fungal infection in an immunological memory lens
J Sharma, S Mudalagiriyappa… - Frontiers in …, 2022 - frontiersin.org
In recent years, fungal vaccine research emanated significant findings in the field of
antifungal T-cell immunity. The generation of effector T cells is essential to combat many …
antifungal T-cell immunity. The generation of effector T cells is essential to combat many …
Haploidentical stem cell transplantation for acute myeloid leukemia: current therapies, challenges and future prospective
YJ Chang, XY Zhao, XJ Huang - Frontiers in Oncology, 2021 - frontiersin.org
Haploidentical stem cell transplantation (haplo-SCT), an alternative donor source, offers a
curative therapy for patients with acute myeloid leukemia (AML) who are transplant …
curative therapy for patients with acute myeloid leukemia (AML) who are transplant …
Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant
JD Rubinstein, C Lutzko, T Leemhuis, X Zhu… - Blood …, 2022 - ashpublications.org
Infections with double-stranded DNA viruses are a significant cause of morbidity and
mortality in pediatric patients following allogeneic hematopoietic stem cell transplantation …
mortality in pediatric patients following allogeneic hematopoietic stem cell transplantation …
[HTML][HTML] Pathogen-specific T cells: targeting old enemies and new invaders in transplantation and beyond
A Papadopoulou, M Alvanou, G Karavalakis… - …, 2023 - journals.lww.com
Adoptive immunotherapy with virus-specific cytotoxic T cells (VSTs) has evolved over the
last three decades as a strategy to rapidly restore virus-specific immunity to prevent or treat …
last three decades as a strategy to rapidly restore virus-specific immunity to prevent or treat …
Virus specific T cell therapy to treat refractory viral infections in solid organ transplant recipients
L Schweitzer, P Muranski - American Journal of Transplantation, 2024 - Elsevier
Solid organ transplant recipients require ongoing immunosuppression to prevent acute
rejection, which puts them at risk for opportunistic infections. Viral infections are particularly …
rejection, which puts them at risk for opportunistic infections. Viral infections are particularly …