Bacteria of the Streptomyces genus constitute an authentic biotech gold mine thanks to their
ability to produce a myriad of compounds and enzymes of great interest at various clinical …

Streptomyces venezuelae is a Gram-positive, filamentous actinomycete with a complex
developmental life cycle. Genomic analysis revealed that S. venezuelae encodes a large …

The Ras superfamily of small GTPases are single domain nucleotide-dependent molecular
switches that act as highly tuned regulators of complex signal transduction pathways …

Streptomycetes are filamentous bacteria that differentiate by producing spore-bearing
reproductive structures called aerial hyphae. The transition from vegetative to reproductive …

Streptomycetes are multicellular bacteria with complex developmental cycles. They are of
biotechnological importance as they produce most bioactive compounds used in …

Genome mining of cyslabdan-producing Streptomyces cyslabdanicus K04-0144 revealed
that a set of four genes, cldA, cldB, cldC, and cldD (the cld cluster), which formed a single …

The characterization of potential gene clusters is a promising strategy for the identification of
novel natural products and the expansion of structural diversity. However, there are often …

In the genus Streptomyces, carbon utilization is of significant importance for the expression
of genes involved in morphological differentiation and antibiotic production. However, there …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a serious threat to global
public health. Fluoroquinolones (FQs) are effective against M. tuberculosis; however …

Actinobacteria are common soil inhabitants and are known to be involved in organic matter
recycling (Bhatti et al., 2017). They have also been well known as a chemically prolific …