An overview of lipoxygenase inhibitors with approach of in vivo studies
A Orafaie, M Mousavian, H Orafai… - Prostaglandins & Other …, 2020 - Elsevier
Lipoxygenases (LOXs) are enzymes which found in organisms that catalyze the
peroxidation of polyunsaturated fatty acids (Arachidonic acid, Linoleic acid). The key role of …
peroxidation of polyunsaturated fatty acids (Arachidonic acid, Linoleic acid). The key role of …
[HTML][HTML] Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation …
P Karimi, MS Ghahfarroki, Z Lorigooini… - Frontiers in …, 2024 - frontiersin.org
Introduction: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition.
Maternal separation (MS) stress is an early-life stress factor associated with behaviors …
Maternal separation (MS) stress is an early-life stress factor associated with behaviors …
[HTML][HTML] Therapeutic mechanism of Toujie Quwen granules in COVID-19 based on network pharmacology
Y Huang, W Zheng, Y Ni, M Li, J Chen, X Liu, X Tan… - BioData mining, 2020 - Springer
Abstract Background Chinese medicine Toujie Quwen granule (TJQW) has proven to be
effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases by relieving …
effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases by relieving …
Anti‐Inflammatory Activity of Ferula assafoetida Oleo‐Gum‐Resin (Asafoetida) against TNF‐α‐Stimulated Human Umbilical Vein Endothelial Cells (HUVECs)
L Mobasheri, M Khorashadizadeh… - Mediators of …, 2022 - Wiley Online Library
Inflammation is the body's biological reaction to endogenous and exogenous stimuli. Recent
studies have demonstrated several anti‐inflammatory properties of Ferula species. In this …
studies have demonstrated several anti‐inflammatory properties of Ferula species. In this …
[HTML][HTML] Comparative evaluation of the protective effects of oral administration of auraptene and umbelliprenin against CFA-induced chronic inflammation with …
This study aimed to evaluate the anti-inflammatory effect of Auraptene (AUR) and
Umbelliprenin (UMB) in a rat model of rheumatoid arthritis (RA) induced by using complete …
Umbelliprenin (UMB) in a rat model of rheumatoid arthritis (RA) induced by using complete …
Umbelliprenin relieves paclitaxel-induced neuropathy
J Shahraki, R Rezaee… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives Umbelliprenin (UMB) is a prenylated coumarin that acts as an in vitro antioxidant
and inhibits lipoxygenase managing the inflammation pathways, while in vivo it exerts anti …
and inhibits lipoxygenase managing the inflammation pathways, while in vivo it exerts anti …
Auraptene Promotes THP-1 Polarization to M1 Macrophages and Improves M1 Function
A Jalali, M Haji Molla Hoseini… - Research Journal of …, 2022 - rjpharmacognosy.ir
Background and Objectives: Macrophages play an important role in tumor growth (M2
macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin …
macrophage) or suppression (M1 macrophage). Auraptene, a prenyloxycoumarin …
[PDF][PDF] Dietary Coumarins 35
Dietary phytochemicals are bioactive components of plant-based foods (phytofoods), eg,
fruits, vegetables, grains, and tea. Their regular and adequate intake may offer protection …
fruits, vegetables, grains, and tea. Their regular and adequate intake may offer protection …