Even if a species' phenotype does not change over evolutionary time, the underlying
mechanism may change, as distinct molecular pathways can realize identical phenotypes …

Aleksandra Chertkova and colleagues [9] employed in silico evolution of Drosophila gap
gene regulatory sequence to demonstrate that elevated mutational pressure leads to …

Efficient network inference is one of the challenges of current-day biology. Its application to
the study of development has seen noteworthy success, yet a multicellular context, tissue …

Background The gap gene system controls the early cascade of the segmentation pathway
in Drosophila melanogaster as well as other insects. Owing to its tractability and key role in …

Changes to promoter regions probably have been responsible for many morphological
evolutionary transitions, especially in animals. This idea is becoming testable, as data from …

Bayesian methods offer a way of doing a fully probabilistic analysis for inference problems
and for dealing with uncertainty. They offer a number of advantages over more conventional …

Публикации официального оппонента к.б.н. Константина Николаевича Коз Page 1
Публикации официального оппонента к.б.н. Константина Николаевича Козлова по теме …

Advances in molecular and developmental biology have lead to the understanding that
many phenotypic traits are the product of many interacting genes, often in the form of gene …

Email: achechkin@ kipt. kharkov. ua A growing number of biological, soft, and active matter
systems are observed to exhibit normal diffusive dynamics with a linear growth of the mean …

We model purifying evolution on the gap gene network, which is a class of genes controlling
early development of Drosophila melanogaster. The simulation algorithm includes …