COUP-TFII in health and disease
S Polvani, S Pepe, S Milani, A Galli - Cells, 2019 - mdpi.com
The nuclear receptors (NRs) belong to a vast family of evolutionary conserved proteins
acting as ligand-activated transcription factors. Functionally, NRs are essential in …
acting as ligand-activated transcription factors. Functionally, NRs are essential in …
Relationships between breast feeding and breast cancer subtypes: lessons learned from studies in humans and in mice
CB Ambrosone, MJ Higgins - Cancer research, 2020 - AACR
There are differential risk relationships between parity and breast cancer according to
estrogen receptor (ER) status, with an increased risk of ER− disease reduced by …
estrogen receptor (ER) status, with an increased risk of ER− disease reduced by …
[HTML][HTML] LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network
Y Zhang, YX Huang, DL Wang, B Yang, HY Yan… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: The forkhead box A1 (FOXA1) is a crucial transcription factor in initiation and
development of breast, lung and prostate cancer. Previous studies about the FOXA1 …
development of breast, lung and prostate cancer. Previous studies about the FOXA1 …
A radiogenomics application for prognostic profiling of endometrial cancer
EA Hoivik, E Hodneland, JA Dybvik… - Communications …, 2021 - nature.com
Prognostication is critical for accurate diagnosis and tailored treatment in endometrial
cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance …
cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance …
The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression
X Xia, C Huang, Y Liao, Y Liu, J He, Z Shao, T Hu… - Cell death & …, 2021 - nature.com
Breast cancer has the highest incidence and mortality in women worldwide. There are 70%
of breast cancers considered as estrogen receptor α (ERα) positive. Therefore, the ERα …
of breast cancers considered as estrogen receptor α (ERα) positive. Therefore, the ERα …
[HTML][HTML] Functional roles of antisense enhancer RNA for promoting prostate cancer progression
Abstract Rationale: Enhancer RNA (eRNA) bi-directionally expresses from enhancer region
and sense eRNA regulates adjacent mRNA in cis and in trans. However, it has remained …
and sense eRNA regulates adjacent mRNA in cis and in trans. However, it has remained …
[HTML][HTML] UCH-L1-mediated down-regulation of estrogen receptor α contributes to insensitivity to endocrine therapy for breast cancer
XS Chen, KS Wang, W Guo, LY Li, P Yu, XY Sun… - Theranostics, 2020 - ncbi.nlm.nih.gov
Purpose: To determine the role of UCH-L1 in regulating ERα expression, and to evaluate
whether therapeutic targeting of UCH-L1 can enhance the efficacy of anti-estrogen therapy …
whether therapeutic targeting of UCH-L1 can enhance the efficacy of anti-estrogen therapy …
Potential regulation of miRNA-29 and miRNA-9 by estrogens in neurodegenerative disorders: An insightful perspective
Finding a link between a hormone and microRNAs (miRNAs) is of great importance since it
enables the adjustment of genetic composition or cellular functions without needing gene …
enables the adjustment of genetic composition or cellular functions without needing gene …
A multi-tissue transcriptomic landscape of female mice in estrus and diestrus provides clues for precision medicine
Y Zhou, H Yan, W Liu, C Hu, Y Zhou, R Sun… - Frontiers in Cell and …, 2022 - frontiersin.org
Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-
primate mammals, respectively, dominates the reproductive processes in non-pregnant …
primate mammals, respectively, dominates the reproductive processes in non-pregnant …
Chromatin organization and transcriptional programming of breast cancer cell identity
JR Bobbitt, DD Seachrist, RA Keri - Endocrinology, 2023 - academic.oup.com
The advent of sequencing technologies for assessing chromosome conformations has
provided a wealth of information on the organization of the 3-dimensional genome and its …
provided a wealth of information on the organization of the 3-dimensional genome and its …