The nuclear receptors (NRs) belong to a vast family of evolutionary conserved proteins
acting as ligand-activated transcription factors. Functionally, NRs are essential in …

There are differential risk relationships between parity and breast cancer according to
estrogen receptor (ER) status, with an increased risk of ER− disease reduced by …

Rationale: The forkhead box A1 (FOXA1) is a crucial transcription factor in initiation and
development of breast, lung and prostate cancer. Previous studies about the FOXA1 …

Prognostication is critical for accurate diagnosis and tailored treatment in endometrial
cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance …

Breast cancer has the highest incidence and mortality in women worldwide. There are 70%
of breast cancers considered as estrogen receptor α (ERα) positive. Therefore, the ERα …

Abstract Rationale: Enhancer RNA (eRNA) bi-directionally expresses from enhancer region
and sense eRNA regulates adjacent mRNA in cis and in trans. However, it has remained …

Purpose: To determine the role of UCH-L1 in regulating ERα expression, and to evaluate
whether therapeutic targeting of UCH-L1 can enhance the efficacy of anti-estrogen therapy …

Finding a link between a hormone and microRNAs (miRNAs) is of great importance since it
enables the adjustment of genetic composition or cellular functions without needing gene …

Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-
primate mammals, respectively, dominates the reproductive processes in non-pregnant …

The advent of sequencing technologies for assessing chromosome conformations has
provided a wealth of information on the organization of the 3-dimensional genome and its …