Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Low yield and low titer of natural products are common issues in natural product
biosynthesis through microbial cell factories. One effective way to resolve such bottlenecks …

A whole-cell biosensor based on synthetic biology provides a promising new method for the
on-site detection of food contaminants. The basic components of whole-cell biosensors …

A variety of chemicals have been produced through metabolic engineering approaches, and
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …

Predictability and robustness are challenges for bioproduction because of the unstable
intracellular synthetic activities. With the deeper understanding of the gene expression …

As biomolecules essential for sustaining life, proteins are generated from long chains of 20
different α‐amino acids that are folded into unique 3D structures. In particular, many proteins …

Highlights•Biosensors responding to metabolites were constructed at genetic level.•The
optimization of biosensors for different targets was summarized.•Biosensors could be …

The microbial communities colonized on microplastics (MPs) have attracted widespread
attention. However, few studies focused on the MPs impacts on mangrove ecosystems …

To overcome environmental problems caused by the use of fossil resources, microbial cell
factories have become a promising technique for the sustainable and eco-friendly …

Genetically encoded biosensors have a diverse range of detectable signals and potential
applications in many fields, including metabolism control and high-throughput screening …