PET imaging in chimeric antigen receptor T-Cell trafficking

P Glennan, V Shehu, SB Singh, TJ Werner, A Alavi… - PET clinics, 2024 - pet.theclinics.com
Chimeric antigen receptor (CAR) T-cell therapy is a form of autologous immunotherapy that
involves the modification of genes to specifically target tumor antigens (Fig. 1). 1 The efficacy …

Optical imaging of in vivo adoptive T‐cell therapy: State of the art and challenges

Q Li, D Hu, D Gao, G Gao, C Zhang, Z Sheng - iRADIOLOGY, 2023 - Wiley Online Library
Adoptive T‐cell therapy (ACT), which is an important type of live cell therapy, has achieved
unprecedented success in treating hematological malignancies. Recent studies have shown …

[HTML][HTML] Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression

W Jiang, G Gu, Y Zhang, Y Song, M Shi, G Wang… - Pharmacological …, 2023 - Elsevier
The design of chimeric antigen receptors (CAR) significantly enhances the antitumor efficacy
of T cells. Although some CAR-T products have been approved by FDA in treating …

Two-site microendoscopic imaging probe for simultaneous three-dimensional imaging at two anatomic locations in tissues

G Liu, SW Ahn, JW Kang, S Bhagavatula, D Matthew… - Optics Letters, 2024 - opg.optica.org
Systems that can image in three dimensions at cellular resolution and across different
locations within an organism may enable insights into complex biological processes, such …