Phages and their potential to modulate the microbiome and immunity
Bacteriophages (hence termed phages) are viruses that target bacteria and have long been
considered as potential future treatments against antibiotic-resistant bacterial infection …
considered as potential future treatments against antibiotic-resistant bacterial infection …
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …
immune and metabolic homeostasis. The microbiome plays a prominent role during …
[HTML][HTML] Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
P Brandi, L Conejero, FJ Cueto, S Martínez-Cano… - Cell Reports, 2022 - cell.com
MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients
against recurrent respiratory infections, including those of viral etiology. However, its …
against recurrent respiratory infections, including those of viral etiology. However, its …
Ecology of the respiratory tract microbiome
A thriving multi-kingdom microbial ecosystem inhabits the respiratory tract: the respiratory
tract microbiome (RTM). In recent years, the contribution of the RTM to human health has …
tract microbiome (RTM). In recent years, the contribution of the RTM to human health has …
Progressive deterioration of the upper respiratory tract and the gut microbiomes in children during the early infection stages of COVID-19
R Xu, P Liu, T Zhang, Q Wu, M Zeng, Y Ma, X Jin… - Journal of Genetics and …, 2021 - Elsevier
Children are less susceptible to coronavirus disease 2019 (COVID-19), and they have
manifested lower morbidity and mortality after infection, for which a multitude of mechanisms …
manifested lower morbidity and mortality after infection, for which a multitude of mechanisms …
[HTML][HTML] Metatranscriptomics to characterize respiratory virome, microbiome, and host response directly from clinical samples
SV Rajagopala, NG Bakhoum, SB Pakala, MH Shilts… - Cell reports …, 2021 - cell.com
We developed a metatranscriptomics method that can simultaneously capture the
respiratory virome, microbiome, and host response directly from low biomass samples …
respiratory virome, microbiome, and host response directly from low biomass samples …
Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma
S Megremis, B Constantinides, P Xepapadaki… - Scientific Reports, 2023 - nature.com
Asthma development and exacerbation is linked to respiratory virus infections. There is
limited information regarding the presence of viruses during non-exacerbation/infection …
limited information regarding the presence of viruses during non-exacerbation/infection …
CRISPR/Cas9-based point-of-care lateral flow biosensor with improved performance for rapid and robust detection of Mycoplasma pneumonia
R Zhu, H Jiang, C Li, Y Li, M Peng, J Wang, Q Wu… - Analytica Chimica …, 2023 - Elsevier
Screening of acute respiratory infections causes serious challenges in urgent point-of-care
scenarios where conventional methods are impractical and alternative techniques suffer …
scenarios where conventional methods are impractical and alternative techniques suffer …
[HTML][HTML] The application of multi-omics in the respiratory microbiome: Progresses, challenges and promises
The study of the respiratory microbiome has entered a multi-omic era. Through integrating
different omic data types such as metagenome, metatranscriptome, metaproteome …
different omic data types such as metagenome, metatranscriptome, metaproteome …
Virome of a feline outbreak of diarrhea and vomiting includes bocaviruses and a novel chapparvovirus
An unexplained outbreak of feline diarrhea and vomiting, negative for common enteric viral
and bacterial pathogens, was subjected to viral metagenomics and PCR. We characterized …
and bacterial pathogens, was subjected to viral metagenomics and PCR. We characterized …