Focus on the Warburg effect, initially descriptive of increased glycolysis in cancer cells, has
served to illuminate mitochondrial function in many other pathologies. This review explores …

Abstract Systems Bioinformatics is a relatively new approach, which lies in the intersection of
systems biology and classical bioinformatics. It focuses on integrating information across …

Spaceflight is known to impose changes on human physiology with unknown molecular
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical …

Outer space is an extremely hostile environment for human life, with ionizing radiation from
galactic cosmic rays and microgravity posing the most significant hazards to the health of …

Humans are integrated with the environment where they live. Gravitational force plays an
important role in shaping the universe, lives, and even cellular biological processes …

Abstract Space environment provides many challenges to pilots, astronauts, and space
scientists, which are constantly subjected to unique conditions, including microgravity …

We investigated the dynamics of immediate and initial gene expression response to different
gravitational environments in human Jurkat T lymphocytic cells and compared expression …

A manned mission to Mars and the establishment of the first human settlement in outer
space was once a mere figment of science fiction but is now being planned and expected to …

The gravitational force has been constant throughout Earth's evolutionary history. Since the
cell nucleus is subjected to permanent forces induced by Earth's gravity, we addressed the …

Background: Ionizing radiation from galactic cosmic rays (GCR) is one of the major risk
factors that will impact the health of astronauts on extended missions outside the protective …