Gas fermentation—a flexible platform for commercial scale production of low-carbon-fuels and chemicals from waste and renewable feedstocks

FM Liew, ME Martin, RC Tappel, BD Heijstra… - Frontiers in …, 2016 - frontiersin.org
There is an immediate need to drastically reduce the emissions associated with global fossil
fuel consumption in order to limit climate change. However, carbon-based materials …

[HTML][HTML] Interbacterial mechanisms of colonization resistance and the strategies pathogens use to overcome them

MT Sorbara, EG Pamer - Mucosal immunology, 2019 - Elsevier
The communities of bacteria that reside in the intestinal tract are in constant competition
within this dynamic and densely colonized environment. At homeostasis, the equilibrium that …

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

D Dodd, MH Spitzer, W Van Treuren, BD Merrill… - Nature, 2017 - nature.com
The human gut microbiota produces dozens of metabolites that accumulate in the
bloodstream,, where they can have systemic effects on the host. Although these small …

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

KM Ng, JA Ferreyra, SK Higginbottom, JB Lynch… - Nature, 2013 - nature.com
The human intestine, colonized by a dense community of resident microbes, is a frequent
target of bacterial pathogens. Undisturbed, this intestinal microbiota provides protection from …

Gut microbes impact stroke severity via the trimethylamine N-oxide pathway

W Zhu, KA Romano, L Li, JA Buffa, N Sangwan… - Cell host & …, 2021 - cell.com
Clinical studies have demonstrated associations between circulating levels of the gut-
microbiota-derived metabolite trimethylamine-N-oxide (TMAO) and stroke incident risk …

Stepping on the gas to a circular economy: accelerating development of carbon-negative chemical production from gas fermentation

N Fackler, BD Heijstra, BJ Rasor… - Annual review of …, 2021 - annualreviews.org
Owing to rising levels of greenhouse gases in our atmosphere and oceans, climate change
poses significant environmental, economic, and social challenges globally. Technologies …

Genome editing in bacteria: CRISPR-Cas and beyond

RD Arroyo-Olarte, R Bravo Rodriguez, E Morales-Ríos - Microorganisms, 2021 - mdpi.com
Genome editing in bacteria encompasses a wide array of laborious and multi-step methods
such as suicide plasmids. The discovery and applications of clustered regularly interspaced …

Fermentative production of butanol—the industrial perspective

EM Green - Current opinion in biotechnology, 2011 - Elsevier
A sustainable bacterial fermentation route to produce biobutanol is poised for re-
commercialization. Today, biobutanol can compete with synthetic butanol in the chemical …

Commercial biomass syngas fermentation

J Daniell, M Köpke, SD Simpson - Energies, 2012 - mdpi.com
The use of gas fermentation for the production of low carbon biofuels such as ethanol or
butanol from lignocellulosic biomass is an area currently undergoing intensive research and …

The role of toxin A and toxin B in Clostridium difficile infection

SA Kuehne, ST Cartman, JT Heap, ML Kelly… - Nature, 2010 - nature.com
Clostridium difficile infection is the leading cause of healthcare-associated diarrhoea in
Europe and North America,. During infection, C. difficile produces two key virulence …