Cerebral blood vessel damage in traumatic brain injury
Traumatic brain injury is a devastating cause of death and disability. Although injury of brain
tissue is of primary interest in head trauma, nearly all significant cases include damage of …
tissue is of primary interest in head trauma, nearly all significant cases include damage of …
Chemokine signaling mediated monocyte infiltration affects anxiety-like behavior following blast injury
The activation of resident microglia and infiltrated monocytes are known potent mediators of
chronic neuroinflammation following traumatic brain injury (TBI). In this study, we use a …
chronic neuroinflammation following traumatic brain injury (TBI). In this study, we use a …
A 3-D rat brain model for blast-wave exposure: effects of brain vasculature and material properties
G Unnikrishnan, H Mao, A Sundaramurthy… - Annals of Biomedical …, 2019 - Springer
Exposure to blast waves is suspected to cause primary traumatic brain injury. However,
existing finite-element (FE) models of the rat head lack the necessary fidelity to characterize …
existing finite-element (FE) models of the rat head lack the necessary fidelity to characterize …
Cerebral vasculature influences blast-induced biomechanical responses of human brain tissue
DR Subramaniam, G Unnikrishnan… - … in bioengineering and …, 2021 - frontiersin.org
Multiple finite-element (FE) models to predict the biomechanical responses in the human
brain resulting from the interaction with blast waves have established the importance of …
brain resulting from the interaction with blast waves have established the importance of …
A strain rate-dependent constitutive model for Göttingen Minipig cerebral arteries
Computational simulations of traumatic brain injury (TBI) are commonly used to advance
understanding of the injury–pathology relationship, tissue damage thresholds, and design of …
understanding of the injury–pathology relationship, tissue damage thresholds, and design of …
Quantitative electroencephalography in a swine model of blast-induced brain injury
C Chen, C Zhou, JM Cavanaugh, S Kallakuri, A Desai… - Brain Injury, 2017 - Taylor & Francis
Objective: Electroencephalography (EEG) was used to examine brain activity abnormalities
earlier after blast exposure using a swine model to develop a qEEG data analysis protocol …
earlier after blast exposure using a swine model to develop a qEEG data analysis protocol …
A 3-D finite-element minipig model to assess brain biomechanical responses to blast exposure
Despite years of research, it is still unknown whether the interaction of explosion-induced
blast waves with the head causes injury to the human brain. One way to fill this gap is to use …
blast waves with the head causes injury to the human brain. One way to fill this gap is to use …
The effect of three-dimensional whole, major, and small vasculature on mouse brain strain under both diffuse and focal brain injury loading
Blood vessels are much stiffer than brain parenchyma and their effects in finite element (FE)
brain models need to be investigated. Despite the publication of some comprehensive three …
brain models need to be investigated. Despite the publication of some comprehensive three …
Elucidating the role of compression waves and impact duration for generating mild traumatic brain injury in rats
BP Lucke-Wold, M Phillips, RC Turner, AF Logsdon… - Brain injury, 2017 - Taylor & Francis
Abstract Background: In total, 3.8 million concussions occur each year in the US leading to
acute functional deficits, but the underlying histopathologic changes that occur are relatively …
acute functional deficits, but the underlying histopathologic changes that occur are relatively …
Characterization of closed head impact injury in rat
The closed head impact (CHI) rat models are commonly used for studying the traumatic
brain injury. The impact parameters vary considerably among different laboratories, making …
brain injury. The impact parameters vary considerably among different laboratories, making …