Merging machine learning and bioelectronics for closed-loop control of biological systems and homeostasis

M Jafari, G Marquez, H Dechiraju, M Gomez… - Cell Reports Physical …, 2023 - cell.com
The regulation of most physiological processes relies on a state of equilibrium called
homeostasis, which is achieved through a biological control loop involving sensors and …

[HTML][HTML] Interpretation of stochastic electrochemical data

SS Jamali, Y Wu, AM Homborg, SG Lemay… - Current Opinion in …, 2024 - Elsevier
Stochastic electrochemical measurement has come of age as a powerful analytical tool in
corrosion science, electrophysiology, and single-entity electrochemistry. It relies on the …

The role of machine learning in advancing precision medicine with feedback control

K Zlobina, M Jafari, M Rolandi, M Gomez - Cell Reports Physical Science, 2022 - cell.com
The capacity of machine-learning methods to handle large and complex datasets makes
them suitable for applications in precision medicine. Current methods automate data …

Integrating Ion Channels with Bioelectronics for Biotic–Abiotic Systems

Y Park, L Luo, M Rolandi - Advanced Intelligent Systems, 2023 - Wiley Online Library
Precise and highly regulated flow of biomolecules and ions through complex cellular
networks is crucial for communication and information processing in living systems. In …

Programmable delivery of fluoxetine via wearable bioelectronics for wound healing in vivo

H Li, H Yang, N Asefifeyzabadi… - Advanced Materials …, 2024 - Wiley Online Library
The ability to deliver drugs with precise dosages at specific time points can significantly
improve disease treatment while reducing side effects. Drug encapsulation for gradual …

The importance of electrode material in bioelectronic electrophoretic ion pumps

T Nguyen, N Asefifeyzabadi, H Li… - Advanced Materials …, 2023 - Wiley Online Library
Bioelectronic ion pumps deliver ions and biomolecules from a source to a target biological
system with high spatiotemporal control for bioengineering and regenerative medicine …

[HTML][HTML] Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters

Y Park, S Hernandez, CO Hernandez… - Cell Reports …, 2024 - cell.com
Precise modulation of brain activity is fundamental for the proper establishment and
maturation of the cerebral cortex. To this end, cortical organoids are promising tools to study …

Bioelectronic Delivery of Potassium Ions Controls Membrane Voltage and Growth Dynamics in Bacteria Biofilms

H Dechiraju, Y Li, C Comerci, L Luo… - Biomedical Materials & …, 2024 - Springer
Bioelectrical signaling, or bioelectricity, is crucial in regulating cellular behavior in biological
systems. This signaling, involving ion fluxes and changes in membrane potential (Vmem), is …

A pro‐reparative bioelectronic device for controlled delivery of ions and biomolecules

N Asefifeyzabadi, T Nguyen, H Li, K Zhu… - Wound Repair and …, 2024 - Wiley Online Library
Wound healing is a complex physiological process that requires precise control and
modulation of many parameters. Therapeutic ion and biomolecule delivery has the …

[图书][B] Bioelectronics for Modulating Cell Membrane Potential

H Dechiraju - 2023 - search.proquest.com
Merging electronics with biological systems poses a significant challenge due to the
fundamental difference between biological signaling, which relies on ions and molecules …