Aging is a complex process associated with nearly all diseases. Understanding the
molecular changes underlying aging and identifying therapeutic targets for aging-related …

Cellular metabolism is a flexible and plastic network that often dictates physiological and
pathological states of the cell, including differentiation, cancer, and aging. Recent advances …

Parkinson's disease (PD) is a neurodegenerative disorder primarily known for typical motor
features that arise due to the loss of dopaminergic neurons in the substantia nigra. However …

A response surface methodology (RSM) and one-factor method were established to
investigate the optimum conditions for the extraction of lychee nuclear polysaccharides …

Senescent neural progenitor cells have been identified in brain lesions of people with
progressive multiple sclerosis (PMS). However, their role in disease pathobiology and …

To understand the dynamic interplay between the human microbiome and host during
health and disease, we analyzed the microbial composition, temporal dynamics, and …

Circadian rhythms are highly conserved biorhythms of~ 24 h that govern many fundamental
biological processes, including cardiovascular (CV) homeostasis. Disrupting the timing of …

Breast cancer is the most prevalent cancer among women in the United States,
representing~ 30% of all new female cancer cases annually. For the year 2024, it is …

Multimorbidity is the co-occurrence of multiple chronic health problems, associated with
aging, frailty, and poor functioning. Children born preterm experience more multimorbid …

Inflammaging, characterized by persistent chronic inflammation in older adults, has emerged
as a critical factor linked to age-related diseases such as cardiovascular diseases (CVDs) …