Update on biology and genomics of adrenocortical carcinomas: rationale for emerging therapies

AM Lerario, DR Mohan, GD Hammer - Endocrine Reviews, 2022 - academic.oup.com
The adrenal glands are paired endocrine organs that produce steroid hormones and
catecholamines required for life. Adrenocortical carcinoma (ACC) is a rare and often fatal …

Primary tumour resection in metastasised adrenocortical carcinoma

CL Viëtor, IJ Schurink, DJ Grünhagen… - Endocrine-Related …, 2025 - erc.bioscientifica.com
Up to 30% of adrenocortical carcinoma (ACC) patients have metastasised disease upon
initial presentation, and systemic treatments currently fail to sufficiently improve survival …

The overall survival and progression-free survival in patients with advanced adrenocortical cancer is increased after the multidisciplinary team evaluation

I Tizianel, M Caccese, F Torresan, G Lombardi… - Cancers, 2022 - mdpi.com
Simple Summary Adrenocortical carcinoma (ACC) is a rare and malignant disease with a
poor prognosis in advanced disease. The complexity of ACC management requires a …

The effect of hormonal secretion on survival in adrenocortical carcinoma: A multi-center study

A Sada, TR Foster, R Al-Ward, S Sawani, HE Charchar… - Surgery, 2024 - Elsevier
Background Current evidence suggests that cortisol secreting adrenocortical carcinoma has
worse prognosis compared to non-secreting adrenocortical carcinoma. However, the effect …

New findings on presentation and outcome of patients with adrenocortical cancer: results from a national cohort study

S Puglisi, A Calabrese, F Ferraù… - The Journal of …, 2023 - academic.oup.com
Context Because of the rarity of adrenocortical cancer (ACC), only a few population-based
studies are available, and they reported limited details in the characterization of patients and …

Case report: Remarkable response to a novel combination of mitotane, etoposide, paraplatin, and sintilimab in a patient with metastatic adrenocortical carcinoma

Y Weng, L Wang, XY Wang, XX Fan, L Yan… - Frontiers in …, 2023 - frontiersin.org
Background Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis
and limited treatment options for metastases. However, new effective regimens are …

Surgery for advanced adrenal malignant disease: recommendations based on European Society of Endocrine Surgeons consensus meeting

R Mihai, C De Crea, C Guerin, F Torresan… - British Journal of …, 2024 - academic.oup.com
Methods A working group established by ESES reviewed the current guidelines and
undertook a literature search of the PubMed database focused on several clinical questions …

[PDF][PDF] Prognostic factors and mitotane treatment of adrenocortical cancer. Two decades of experience from an institutional case series

J Toke, A Uhlyarik, J Lohinszky, J Stark… - Front Endocrinol …, 2022 - academia.edu
Objectives: This study aimed to characterise the clinicopathological features and prognostic
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …

The effect of adrenalectomy on overall survival in metastatic adrenocortical carcinoma

A Assad, RB Incesu, S Morra… - The Journal of …, 2024 - academic.oup.com
Context Although complete surgical resection provides the only means of cure in
adrenocortical carcinoma (ACC), the magnitude of the survival benefit of adrenalectomy in …

Prognostic factors and mitotane treatment of adrenocortical cancer. Two decades of experience from an institutional case series

J Tőke, A Uhlyarik, J Lohinszky, J Stark… - Frontiers in …, 2022 - frontiersin.org
Objectives This study aimed to characterise the clinicopathological features and prognostic
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …