Update on biology and genomics of adrenocortical carcinomas: rationale for emerging therapies
The adrenal glands are paired endocrine organs that produce steroid hormones and
catecholamines required for life. Adrenocortical carcinoma (ACC) is a rare and often fatal …
catecholamines required for life. Adrenocortical carcinoma (ACC) is a rare and often fatal …
Primary tumour resection in metastasised adrenocortical carcinoma
CL Viëtor, IJ Schurink, DJ Grünhagen… - Endocrine-Related …, 2025 - erc.bioscientifica.com
Up to 30% of adrenocortical carcinoma (ACC) patients have metastasised disease upon
initial presentation, and systemic treatments currently fail to sufficiently improve survival …
initial presentation, and systemic treatments currently fail to sufficiently improve survival …
The overall survival and progression-free survival in patients with advanced adrenocortical cancer is increased after the multidisciplinary team evaluation
I Tizianel, M Caccese, F Torresan, G Lombardi… - Cancers, 2022 - mdpi.com
Simple Summary Adrenocortical carcinoma (ACC) is a rare and malignant disease with a
poor prognosis in advanced disease. The complexity of ACC management requires a …
poor prognosis in advanced disease. The complexity of ACC management requires a …
The effect of hormonal secretion on survival in adrenocortical carcinoma: A multi-center study
A Sada, TR Foster, R Al-Ward, S Sawani, HE Charchar… - Surgery, 2024 - Elsevier
Background Current evidence suggests that cortisol secreting adrenocortical carcinoma has
worse prognosis compared to non-secreting adrenocortical carcinoma. However, the effect …
worse prognosis compared to non-secreting adrenocortical carcinoma. However, the effect …
New findings on presentation and outcome of patients with adrenocortical cancer: results from a national cohort study
S Puglisi, A Calabrese, F Ferraù… - The Journal of …, 2023 - academic.oup.com
Context Because of the rarity of adrenocortical cancer (ACC), only a few population-based
studies are available, and they reported limited details in the characterization of patients and …
studies are available, and they reported limited details in the characterization of patients and …
Case report: Remarkable response to a novel combination of mitotane, etoposide, paraplatin, and sintilimab in a patient with metastatic adrenocortical carcinoma
Y Weng, L Wang, XY Wang, XX Fan, L Yan… - Frontiers in …, 2023 - frontiersin.org
Background Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis
and limited treatment options for metastases. However, new effective regimens are …
and limited treatment options for metastases. However, new effective regimens are …
Surgery for advanced adrenal malignant disease: recommendations based on European Society of Endocrine Surgeons consensus meeting
Methods A working group established by ESES reviewed the current guidelines and
undertook a literature search of the PubMed database focused on several clinical questions …
undertook a literature search of the PubMed database focused on several clinical questions …
[PDF][PDF] Prognostic factors and mitotane treatment of adrenocortical cancer. Two decades of experience from an institutional case series
J Toke, A Uhlyarik, J Lohinszky, J Stark… - Front Endocrinol …, 2022 - academia.edu
Objectives: This study aimed to characterise the clinicopathological features and prognostic
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …
The effect of adrenalectomy on overall survival in metastatic adrenocortical carcinoma
A Assad, RB Incesu, S Morra… - The Journal of …, 2024 - academic.oup.com
Context Although complete surgical resection provides the only means of cure in
adrenocortical carcinoma (ACC), the magnitude of the survival benefit of adrenalectomy in …
adrenocortical carcinoma (ACC), the magnitude of the survival benefit of adrenalectomy in …
Prognostic factors and mitotane treatment of adrenocortical cancer. Two decades of experience from an institutional case series
J Tőke, A Uhlyarik, J Lohinszky, J Stark… - Frontiers in …, 2022 - frontiersin.org
Objectives This study aimed to characterise the clinicopathological features and prognostic
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …
factors of a large cohort of Hungarian patients with adrenocortical cancer diagnosed …