Alzheimer's disease (AD) is a disorder that causes degeneration of the cells in the brain and
it is the main cause of dementia, which is characterized by a decline in thinking and …

Clinicians can encounter sex and gender disparities in diagnostic and therapeutic
responses. These disparities are noted in epidemiology, pathophysiology, clinical …

Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

As machine learning methods gain prominence within clinical decision-making, the need to
address fairness concerns becomes increasingly urgent. Despite considerable work …

AD is a neurodegenerative disease, and its frequency is often reported to be higher for
women than men: almost two-thirds of patients with AD are women. One prevailing view is …

Importance It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are
at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent …

Objective To test the hypothesis that distinct subtypes of Alzheimer disease (AD) exist and
underlie the heterogeneity within AD, we conducted a systematic review and meta-analysis …

All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …

After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …