Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Disentangling host–microbiota complexity through hologenomics

A Alberdi, SB Andersen, MT Limborg, RR Dunn… - Nature Reviews …, 2022 - nature.com
Research on animal–microbiota interactions has become a central topic in biological
sciences because of its relevance to basic eco-evolutionary processes and applied …

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

S Han, W Van Treuren, CR Fischer, BD Merrill… - Nature, 2021 - nature.com
Gut microorganisms modulate host phenotypes and are associated with numerous health
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

GZ Wei, KA Martin, PY Xing… - Proceedings of the …, 2021 - National Acad Sciences
While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

Dissecting the contribution of host genetics and the microbiome in complex behaviors

SA Buffington, SW Dooling, M Sgritta, C Noecker… - Cell, 2021 - cell.com
The core symptoms of many neurological disorders have traditionally been thought to be
caused by genetic variants affecting brain development and function. However, the gut …

The impact of aging-induced gut microbiome dysbiosis on dendritic cells and lung diseases

JA Malik, MA Zafar, T Lamba, S Nanda, MA Khan… - Gut …, 2023 - Taylor & Francis
Aging is an inevitable natural process that impacts every individual, and understanding its
effect on the gut microbiome and dendritic cell (DC) functionality in elderly subjects is …

Gut microbiome modulates Drosophila aggression through octopamine signaling

Y Jia, S Jin, K Hu, L Geng, C Han, R Kang… - Nature …, 2021 - nature.com
Gut microbiome profoundly affects many aspects of host physiology and behaviors. Here we
report that gut microbiome modulates aggressive behaviors in Drosophila. We found that …

The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

E Jašarević, EM Hill, PJ Kane, L Rutt, T Gyles… - Nature …, 2021 - nature.com
Newborns are colonized by maternal microbiota that is essential for offspring health and
development. The composition of these pioneer communities exhibits individual differences …

[HTML][HTML] Gut microbiota and immunity relevance in eubiosis and dysbiosis

HE Al-Rashidi - Saudi journal of biological sciences, 2022 - Elsevier
Human gut is colonized by numerous microorganisms, in which bacteria present the highest
proportion of this colonization that live in a symbiotic relationship with the host. This …

Advances in bulk and single-cell multi-omics approaches for systems biology and precision medicine

Y Li, L Ma, D Wu, G Chen - Briefings in Bioinformatics, 2021 - academic.oup.com
Multi-omics allows the systematic understanding of the information flow across different
omics layers, while single omics can mainly reflect one aspect of the biological system. The …