Diagnosis and treatment of primary aldosteronism
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …
The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2019)
S Umemura, H Arima, S Arima, K Asayama… - Hypertension …, 2019 - nature.com
The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …
Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension: the target-HTN randomized clinical trial
Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …
Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the working group on endocrine hypertension of …
Autonomous aldosterone overproduction represents the underlying condition of 5–10% of
patients with arterial hypertension and carries a significant burden of mortality and morbidity …
patients with arterial hypertension and carries a significant burden of mortality and morbidity …
Aldosterone as a mediator of cardiovascular damage
Besides the physiological regulation of water, sodium, and potassium homeostasis,
aldosterone modulates several physiological and pathological processes in the …
aldosterone modulates several physiological and pathological processes in the …
Primary aldosteronism—a multidimensional syndrome
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
Testing for primary aldosteronism and mineralocorticoid receptor antagonist use among US veterans: a retrospective cohort study
Background: Primary aldosteronism is a common cause of treatment-resistant hypertension.
However, evidence from local health systems suggests low rates of testing for primary …
However, evidence from local health systems suggests low rates of testing for primary …
The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …
Primary aldosteronism: state-of-the-art review
A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
Pathogenesis and treatment of primary aldosteronism
MC Zennaro, S Boulkroun… - Nature Reviews …, 2020 - nature.com
Early diagnosis and appropriate treatment of primary aldosteronism, the most frequent
cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …
cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …