Introduction: Chagas disease (CD) is a neglected disease caused by the protozoan parasite
Trypanosoma cruzi. In terms of novel drug discovery, there has been no progress since the …

Schistosomiasis is a neglected tropical disease affecting over 250 million people worldwide.
The disease is the second most prevalent neglected tropical disease after malaria …

In tropical and sub-tropical areas of the world the most damaging pest of the livestock sector
are cattle tick, Rhipicephalus microplus. The current study was aimed to generate …

Chemotherapy is the most widely advocated method of Schistosome control. However,
repeated chemotherapy leads to the emergence of drug-resistant Schistosoma strains …

In this study, the inhibitory potential of four pyrethroid compounds on glutathione S-
transferase (GST) by using molecular docking and in vitro assays was evaluated. Docking …

Small-molecule compounds that have promising activity against macromolecular targets
from Trypanosoma cruzi occasionally fail when tested in whole-cell phenotypic assays. This …

Malaria, caused by Plasmodium protozoa with Plasmodium falciparum as the most virulent
species, continues to pose significant health challenges. Despite the availability of effective …

Limonene and perillyl alcohol are natural monoterpenes that have attracted the attention of
medicinal chemists due to their promising anticancer activities. Considering this, both …

Background: Schiff bases are synthetically accessible compounds that have been used in
medicinal chemistry. Methods & results: In this work, 27 Schiff bases derived from …

Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications,
including neurotoxoplasmosis, a leading cause of cerebral lesions in AIDS patients. The …