Statin-associated muscle symptoms (SAMS) are one of the principal reasons for statin non-
adherence and/or discontinuation, contributing to adverse cardiovascular outcomes. This …

Statins are highly effective for preventing cardiovascular events by reducing low-density
lipoprotein cholesterol (LDL-C). However, many patients taking statins report muscle-related …

Importance Muscle-related statin intolerance is reported by 5% to 20% of patients. Objective
To identify patients with muscle symptoms confirmed by statin rechallenge and compare …

Context The use of acid-suppressive medication has been steadily increasing, particularly in
the inpatient setting, despite lack of an accepted indication in the majority of these patients …

Statin-related myopathy is a clinically important cause of statin intolerance and
discontinuation. The spectrum of statin-related myopathy ranges from common but clinically …

Introduction: Statin-induced myopathy is an important cause of statin intolerance and the
most common cause of statin discontinuation. Observational studies estimate that 10–15 …

Background: Red yeast rice is an herbal supplement that decreases low-density lipoprotein
(LDL) cholesterol level. Objective: To evaluate the effectiveness and tolerability of red yeast …

Although statins are remarkably effective, they are still underprescribed because of concerns
about muscle toxicity. We review the aspects of statin myopathy that are important to the …

Statins are considered very effective in reducing cardiovascular morbidity and mortality in
high-risk patients. However, although adherence to statins improves morbidity and mortality …

Background Once-daily, oral ETC-1002 reduces low-density lipoprotein cholesterol (LDL-C)
and has beneficial effects on other cardiometabolic risk factors but has not been examined …