The role of extracellular matrix (ECM) adhesion motifs in functionalised hydrogels

AJ Morwood, IA El-Karim, SA Clarke, FT Lundy - Molecules, 2023 - mdpi.com
To create functional tissue engineering scaffolds, biomaterials should mimic the native
extracellular matrix of the tissue to be regenerated. Simultaneously, the survival and …

Progress in 3D bioprinting technology for osteochondral regeneration

M Lafuente-Merchan, S Ruiz-Alonso, F García-Villén… - Pharmaceutics, 2022 - mdpi.com
Osteochondral injuries can lead to osteoarthritis (OA). OA is characterized by the
progressive degradation of the cartilage tissue together with bone tissue turnover …

Ultrasound Stimulation of Piezoelectric Nanocomposite Hydrogels Boosts Chondrogenic Differentiation in Vitro, in Both a Normal and Inflammatory Milieu

L Ricotti, A Cafarelli, C Manferdini, D Trucco… - ACS …, 2024 - ACS Publications
The use of piezoelectric nanomaterials combined with ultrasound stimulation is emerging as
a promising approach for wirelessly triggering the regeneration of different tissue types …

Mesenchymal stromal cells laden in hydrogels for osteoarthritis cartilage regeneration: A systematic review from in vitro studies to clinical applications

C Manferdini, E Gabusi, Y Saleh, E Lenzi, G D'Atri… - Cells, 2022 - mdpi.com
This systematic review is focused on the main characteristics of the hydrogels used for
embedding the mesenchymal stromal cells (MSCs) in in vitro/ex vivo studies, in vivo OA …

Cell‐instructive biomaterials in tissue engineering and regenerative medicine

B Adhikari, MA Stager, MD Krebs - Journal of Biomedical …, 2023 - Wiley Online Library
The field of biomaterials aims to improve regenerative outcomes or scientific understanding
for a wide range of tissue types and ailments. Biomaterials can be fabricated from natural or …

Strategy insight: Mechanical properties of biomaterials' influence on hydrogel-mesenchymal stromal cell combination for osteoarthritis therapy

H Ying, C Shen, R Pan, X Li, Y Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Osteoarthritis (OA) is a kind of degenerative joint disease usually found in older adults and
those who have received meniscal surgery, bringing great suffering to a number of patients …

Editorial on the Special Issue “Modification of Hydrogels and Their Applications in Biomedical Engineering”

Y Wang, Q Wei - Gels, 2023 - mdpi.com
Hydrogels and hydrophilic polymer networks play an important role in biomedical
engineering due to their good biocompatibility, biodegradability, hydrophilicity, and …

[HTML][HTML] Visible light-mediated cross-linking of injectable gellan gum hydrogels embedding human chondrocytes

D Trucco, L Vannozzi, E Gabusi, E Lenzi… - Carbohydrate Polymer …, 2023 - Elsevier
Gellan gum, a polysaccharide with structural similarities to glycosaminoglycans, is gaining
attention in cartilage tissue engineering. It can be chemically modified with methacrylic …

Autophagy is a crucial path in chondrogenesis of adipose-derived mesenchymal stromal cells laden in hydrogel

E Gabusi, E Lenzi, C Manferdini, P Dolzani… - Gels, 2022 - mdpi.com
Autophagy is a cellular process that contributes to the maintenance of cell homeostasis
through the activation of a specific path, by providing the necessary factors in stressful and …

[PDF][PDF] Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel. Gels 2022, 8, 766

E Gabusi, E Lenzi, C Manferdini, P Dolzani… - 2022 - academia.edu
Autophagy is a cellular process that contributes to the maintenance of cell homeostasis
through the activation of a specific path, by providing the necessary factors in stressful and …