Diabetic macular edema (DME) is the major cause of vision loss in diabetic persons.
Alteration of the blood–retinal barrier is the hallmark of this disease, characterized by …

Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic
retinopathy, age-related macular degeneration, retinal vein occlusions, uveitis and other …

Protein kinase C (PKC) has been a tantalizing target for drug discovery ever since it was first
identified as the receptor for the tumour promoter phorbol ester in 1982. Although initial …

Both cardio-and microvascular complications adversely affect the life quality of patients with
diabetes and have been the leading cause of mortality and morbidity in this population …

Background Laser treatment for diabetic retinopathy is often associated with visual field
reduction and other ocular side-effects. Our aim was to assess whether long-term lipid …

ContextDiabetic retinopathy (DR) is the leading cause of blindness in the working-aged
population in the United States. There are many new interventions for DR, but evidence to …

PURPOSE: To report the findings at 1 year of a study comparing repeated intravitreal
bevacizumab (ivB) and modified Early Treatment of Diabetic Retinopathy Study (ETDRS) …

The prevalence of diabetes worldwide is increasing rapidly in association with the increase
in obesity. Complications are a major fear of patients with diabetes. Complications of …

Diabetic retinopathy remains the leading vascular-associated cause of blindness throughout
the world. Its treatment requires a multidisciplinary interventional approach at both systemic …

Microvascular complications (retinopathy, nephropathy, and neuropathy) affect hundreds of
millions of patients with type 2 diabetes. They usually affect people with longstanding or …