HIV-1 infection and cognitive impairment in the cART era: a review

J Schouten, P Cinque, M Gisslen, P Reiss, P Portegies - Aids, 2011 - journals.lww.com
With the introduction of combination antiretroviral therapy AIDS dementia complex or HIV-
associated dementia, as it was termed later, largely disappeared in clinical practice …

Pathogenesis of HIV in the central nervous system

V Valcour, P Sithinamsuwan, S Letendre… - Current Hiv/aids …, 2011 - Springer
HIV can infect the brain and impair central nervous system (CNS) function. Combination
antiretroviral therapy (cART) has not eradicated CNS complications. HIV-associated …

Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era

RA Cohen, J Harezlak, G Schifitto, G Hana… - Journal of …, 2010 - Springer
Cerebral atrophy is a well-described, but poorly understood complication of human
immunodeficiency virus (HIV) infection. Despite reduced prevalence of HIV-associated …

Brain metabolic correlates of persistent olfactory dysfunction after SARS-Cov2 infection

MI Donegani, A Miceli, M Pardini, M Bauckneht… - Biomedicines, 2021 - mdpi.com
We aimed to evaluate the brain hypometabolic signature of persistent isolated olfactory
dysfunction after SARS-CoV-2 infection. Twenty-two patients underwent whole-body [18F] …

HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease?

RA Cohen, TR Seider, B Navia - Alzheimer's research & therapy, 2015 - Springer
Marked improvements in survival and health outcome for people infected with HIV have
occurred since the advent of combination antiretroviral therapy over a decade ago. Yet HIV …

Differentiating HIV-associated neurocognitive disorders from Alzheimer's disease: an emerging issue in geriatric NeuroHIV

B Milanini, V Valcour - Current HIV/AIDS Reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review was to examine characteristics that
may distinguish HIV-associated neurocognitive disorder (HAND) from early Alzheimer's …

HIV-associated neurocognitive impairment in the modern ART era: are we close to discovering reliable biomarkers in the setting of virological suppression?

A Bandera, L Taramasso, G Bozzi… - Frontiers in aging …, 2019 - frontiersin.org
The prevalence of the most severe forms of HIV-associated neurocognitive disorders
(HAND) is decreasing due to worldwide availability and high efficacy of antiretroviral …

Loss of neuronal integrity during progressive HIV-1 infection of humanized mice

PK Dash, S Gorantla, HE Gendelman… - Journal of …, 2011 - Soc Neuroscience
Neuronal damage induced by ongoing human immunodeficiency virus type 1 (HIV-1)
infection was investigated in humanized NOD/scid-IL-2Rγcnull mice transplanted at birth …

Significant effects of antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders

A Borjabad, S Morgello, W Chao, SY Kim… - PLoS …, 2011 - journals.plos.org
Antiretroviral therapy (ART) has reduced morbidity and mortality in HIV-1 infection; however
HIV-1-associated neurocognitive disorders (HAND) persist despite treatment. The reasons …

Regional brain structural dysmorphology in human immunodeficiency virus infection: effects of acquired immune deficiency syndrome, alcoholism, and age

A Pfefferbaum, MJ Rosenbloom, SA Sassoon… - Biological …, 2012 - Elsevier
BACKGROUND: Human immunodeficiency virus (HIV) infection and alcoholism each carries
liability for disruption of brain structure and function integrity. Despite considerable …