The diagnosis of inflammatory bowel disease (IBD) is traditionally based on a combination
of clinical, endoscopic, histological, and radiological criteria. However, further testing is …

Inflammatory bowel disease (IBD) is an enduring disease involving mostly young people,
with symptoms of bloody diarrhea and abdominal cramps. Several antibodies have been …

Background & Aims: Antibody responses to certain microbial antigens define heterogeneous
groups of Crohn's patients; multiple and high-level responses to these antigens are …

Background & Aims: Previous studies in Crohn's disease suggest global loss of tolerance
with sonicated bacteria preparations containing hundreds of antigens. Monoassociation …

Background & Aims: The clinical manifestations of Crohn's disease (CD) are diverse,
ranging from fibrostenosing small-bowel disease to colon-predominant inflammation. These …

OBJECTIVES: Serologic testing is increasingly being utilized to evaluate children with
suspected inflammatory bowel disease (IBD). The aim of this paper was to evaluate the …

Antineutrophil cytoplasmic antibody (ANCA) tests are used to diagnose and monitor
inflammatory activity in Wegener granulomatosis, microscopic polyangiitis and its renal …

The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as
to whether PSC should be denominated an autoimmune disease. A large number of …

Objective Anti-neutrophil cytoplasmic antibodies and anti-Saccharomyces cerevisiae
mannan antibodies (ASCAs) have been detected in the serum of patients with ulcerative …

Although they are one of the oldest family of proteins known (first described in 1884 by
Kossel), histones continue to surprise researchers with their ever expanding roles in biology …