Chronic diseases, inflammation, and spices: how are they linked?

AB Kunnumakkara, BL Sailo, K Banik, C Harsha… - Journal of translational …, 2018 - Springer
Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …

Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

The effects of Nigella sativa on respiratory, allergic and immunologic disorders, evidence from experimental and clinical studies, a comprehensive and updated …

S Saadat, MR Aslani, V Ghorani… - Phytotherapy …, 2021 - Wiley Online Library
Nigella sativa (N. sativa) seed had been used traditionally due to several pharmacological
effects. The updated experimental and clinical effects of N. sativa and its constituents on …

Herbal medicines for rhinosinusitis: A systematic review and network meta-analysis

MP Hoang, K Seresirikachorn… - Current allergy and …, 2023 - Springer
Abstract Purpose of Review To analyze and compare the effects of herbal medicines (HMs)
for treating different forms of rhinosinusitis. Recent Findings Forty-seven randomized …

Effect of Nigella sativa and its bioactive compound on type 2 epithelial to mesenchymal transition: a systematic review

A Nordin, H Kamal, MD Yazid, A Saim… - BMC complementary and …, 2019 - Springer
Background Nigella sativa or commonly known as black seed or black cumin is one of the
most ubiquitous complementary medicine. Epithelial to mesenchymal transition (EMT) of …

Effects of Nigella sativa Extract on Chronic Rhinosinusitis: A Randomized Double Blind Study

S Nemati, M Masroorchehr, H Elahi… - Indian Journal of …, 2021 - Springer
Chronic rhinosinusitis (CRS) causes long-term discomfort for patients, and due to the
frequent relapses and dissatisfaction with current treatments, CRS patients pay more …

[HTML][HTML] The value of Nigella sativa in the treatment of experimentally induced rhinosinusitis

O Yoruk, A Tatar, ON Keles, A Cakir - Acta Otorhinolaryngologica …, 2017 - ncbi.nlm.nih.gov
The aim of this study was to investigate the effect of Nigella sativa and cephalexin in the
therapy of experimental bacterial rhinosinusitis. Bacterial rhinosinusitis was induced with …

A systematic review of randomized controlled trials with herbal medicine on chronic rhinosinusitis

M Anushiravani, M Bakhshaee… - Phytotherapy …, 2018 - Wiley Online Library
Chronic rhinosinusitis (CRS) is a common disease with evidence to show that its incidence
and prevalence are increasing. Medicinal plants are commonly used to treat CRS. This …

Ameliorative Effect of Thymoquinone‐Loaded PLGA Nanoparticles on Chronic Lung Injury Induced by Repetitive Intratracheal Instillation of Lipopolysaccharide in …

SAM Saghir, NA Al-Gabri, AA Ali… - Oxidative Medicine …, 2021 - Wiley Online Library
Thymoquinone (TQ), the active constituent of Nigella sativa, possesses several benefits in
traditional and modern medicines. This study examined the effect of a single dose of Nano …

Effect of Nigella sativa Nasal Spray on the Treatment of Chronic Rhinosinusitis Without a Nasal Polyp

A Rezaeian, S Amoushahi Khouzani - Allergy & Rhinology, 2018 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is a common inflammatory disease of nasal and
paranasal sinuses, with many treatment methods available for the management of this …