Fluorescence correlation spectroscopy (FCS) is a powerful technique for quantification of
molecular dynamics, and it has been widely applied in diverse fields, eg, biomedicine …

Fluorescence correlation spectroscopy (FCS) is a single molecule sensitive tool for the
quantitative measurement of biomolecular dynamics and interactions. Improvements in …

Cells relay a plethora of extracellular signals to specific cellular responses by using only a
few second messengers, such as cAMP. To explain signaling specificity, cAMP-degrading …

Super-resolution optical microscopy is a rapidly evolving area of fluorescence microscopy
with a tremendous potential for impacting many fields of science. Several super-resolution …

The interaction of lipids and proteins plays an important role in plasma membrane
bioactivity, and much can be learned from their diffusion characteristics. Here we present the …

Membrane lateral heterogeneity is accepted as a requirement for the function of biological
membranes and the notion of lipid rafts gives specificity to this broad concept. However, the …

In recent years fluorescence correlation spectroscopy (FCS) has become a routine method
for determining diffusion coefficients, chemical rate constants, molecular concentrations …

Cell biologists strive to characterize molecular interactions directly in the intracellular
environment. The intrinsic resolution of optical microscopy, however, allows visualization of …

Ever since technologies enabled the characterization of eukaryotic plasma membranes,
heterogeneities in the distributions of its constituents were observed. Over the years this led …

Fluorescence correlation spectroscopy (FCS) is a powerful technique to measure
concentrations, mobilities, and interactions of fluorescent biomolecules. It can be applied to …