Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease

M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …

The influence of changing interfaces on aerosol delivery within high flow oxygen setting in adults: an in-vitro study

YM Madney, NI Laz, AA Elberry, H Rabea… - Journal of Drug Delivery …, 2020 - Elsevier
Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

Aerosol delivery through an adult high-flow nasal cannula circuit using low-flow oxygen

YM Madney, M Fathy, AA Elberry, H Rabea… - Respiratory …, 2019 - rc.rcjournal.com
BACKGROUND: There has been a growing trend toward delivering aerosolized medications
using high-flow nasal cannula (HFNC). In some cases, patients who do not require high-flow …

Effects of fill volume and humidification on aerosol delivery during single-limb noninvasive ventilation

H Saeed, M Mohsen, AS Eldin, AA Elberry… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: The aim of this work was to determine the effect of fill volume and
humidification change on aerosol delivery during single-limb noninvasive ventilation (NIV) …

The impact of adding a training device to familiar counselling on inhalation technique and pulmonary function of asthmatics

M Nicola, A Elberry, O Sayed, R Hussein, H Saeed… - Advances in …, 2018 - Springer
Introduction We have investigated the effect of adding a pressurized metered dose inhaler
(pMDI) training device to verbal counselling on pulmonary function and inhalation …

Performance of large spacer versus nebulizer T-piece in single-limb noninvasive ventilation

HS Harb, AA Elberry, H Rabea, M Fathy… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: Predosing patients with COPD with salbutamol by using a pressurized
metered-dose-inhaler (pMDI) as a bronchodilator was hypothesized to improve the …

Towards More Precise Targeting of Inhaled Aerosols to Different Areas of the Respiratory System

TR Sosnowski - Pharmaceutics, 2024 - mdpi.com
Pharmaceutical aerosols play a key role in the treatment of lung disorders, but also systemic
diseases, due to their ability to target specific areas of the respiratory system (RS). This …

Effect of functional principle, delivery technique, and connection used on aerosol delivery from different nebulizers: An in-vitro study

NEE Sayed, MA Abdelrahman… - Pulmonary Pharmacology …, 2021 - Elsevier
Objective Nebulizers can be divided according to their functional principle into jet, ultrasonic
and vibrating mesh nebulizers with intermittent or continuous aerosol delivery and may be …

Effect of different connection adapters on aerosol delivery in invasive ventilation setting; an in-vitro study

SM Seif, MA Elnady, H Rabea, H Saeed… - Journal of Drug Delivery …, 2021 - Elsevier
Introduction Different aerosol generators are used during mechanical ventilation connected
to spacers or adapters. The design and volume of these connections can significantly affect …

Effect of oxygen flow on aerosol delivery from a vibrating mesh nebulizer with a holding chamber

MA Amin, HK Taha, RRS Hussein, RM Sarhan… - Beni-Suef University …, 2022 - Springer
Background A holding chamber (HC) was created to work with a vibrating mesh nebulizer
(VMN) to boost the total inhalable dose for patients. In addition to the optional supply of …