Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Recent Progress in in vitro Models for Atherosclerosis Studies

J Chen, X Zhang, R Millican, T Lynd… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Innovations in stem cell therapy for diabetic wound healing

J Ho, D Yue, U Cheema, HC Hsia… - Advances in Wound …, 2023 - liebertpub.com
Significance: The global burden of diabetic wounds, particularly diabetic foot ulcers,
continues to have large economic and social impact throughout the world. Current strategies …

[HTML][HTML] Preparation and characterization of poly (ethylene oxide)/zinc oxide nanofibrous scaffold for chronic wound healing applications

H Nosrati, M Khodaei… - Polymers in …, 2020 - polimery.umw.edu.pl
Background. Skin, the first barrier to pathogens, loses its integrity and function after an injury.
The presence of an antibacterial dressing at the wound site may prevent bacterial invasion …

Tissue engineering-based strategies for diabetic foot ulcer management

A Chiu, D Sharma, F Zhao - Advances in Wound Care, 2023 - liebertpub.com
Significance: Diabetic foot ulcers (DFU) are a mounting problem with the increasingly frail
population. Injuries that would otherwise heal are kept open by risk factors such as diabetes …

Human iPSC-derived vascular smooth muscle cells in a fibronectin functionalized collagen hydrogel augment endothelial cell morphogenesis

K Duan, BC Dash, DC Sasson, S Islam, J Parker… - Bioengineering, 2021 - mdpi.com
Tissue-engineered constructs have immense potential as autologous grafts for wound
healing. Despite the rapid advancement in fabrication technology, the major limitation is …

Engineering smooth muscle to understand extracellular matrix remodeling and vascular disease

D Yarbrough, S Gerecht - Bioengineering, 2022 - mdpi.com
The vascular smooth muscle is vital for regulating blood pressure and maintaining
cardiovascular health, and the resident smooth muscle cells (SMCs) in blood vessel walls …

An in situ collagen‐HA hydrogel system promotes survival and preserves the proangiogenic secretion of hiPSC‐derived vascular smooth muscle cells

BC Dash, K Duan, H Xing… - Biotechnology and …, 2020 - Wiley Online Library
Human‐induced pluripotent stem cell‐derived vascular smooth muscle cells (hiPSC‐
VSMCs) with proangiogenic properties have huge therapeutic potential. While hiPSC …

Unlocking the potential of induced pluripotent stem cells for wound healing: the next frontier of regenerative medicine

BC Dash, L Korutla, P Vallabhajosyula… - Advances in Wound …, 2022 - liebertpub.com
Significance: Nonhealing wounds are a significant burden for the health care system all over
the world. Existing treatment options are not enough to promote healing, highlighting the …

Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology

CS Kwartler, JE Esparza Pinelo - Arteriosclerosis, Thrombosis, and …, 2024 - Am Heart Assoc
The implementation of human-induced pluripotent stem cell models has introduced an
additional tool for identifying molecular mechanisms of disease that complement animal …