Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone
formation and resorption. The balance between the two phases is crucial for sustaining bone …

During life, bone undergoes modelling and remodelling in order to grow or change shape.
Bone modelling is the process by which bones change shape or size in response to …

Abstract N6-methyladenosine (m6A) is the most abundant epigenetic modification in
eukaryotic mRNAs and is essential for multiple RNA processing events during mammalian …

Calcium is an essential trace element and a vital contributor to numerous reactions in
virtually every human cell. To ensure normal physiologic functions, intracellular and …

The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles
in the maintenance of calcium and phosphate homeostasis as well as the development and …

Physiological bone remodeling is a highly coordinated process responsible for bone
resorption and formation and is necessary to repair damaged bone and to maintain mineral …

Classic endocrine feedback loops ensure the regulation of blood calcium. Calcium in the
extracellular fluid (ECF) binds and activates the calcium sensing receptor (CaSR) on the …

Exercise perturbs homeostasis, alters the levels of circulating mediators and hormones, and
increases the demand by skeletal muscles and other vital organs for energy substrates …

The construction of bioactive peptides using β-amino acid-containing sequence patterns is a
very promising strategy to obtain analogues that exhibit properties of high interest for …