SBML Level 3: an extensible format for the exchange and reuse of biological models

SM Keating, D Waltemath, M König, F Zhang… - Molecular systems …, 2020 - embopress.org
Abstract Systems biology has experienced dramatic growth in the number, size, and
complexity of computational models. To reproduce simulation results and reuse models …

Genetic circuit design automation with Cello 2.0

TS Jones, SMD Oliveira, CJ Myers, CA Voigt… - Nature protocols, 2022 - nature.com
Cells interact with their environment, communicate among themselves, track time and make
decisions through functions controlled by natural regulatory genetic circuits consisting of …

Birth of a Photosynthetic Chassis: A MoClo Toolkit Enabling Synthetic Biology in the Microalga Chlamydomonas reinhardtii

P Crozet, FJ Navarro, F Willmund… - ACS synthetic …, 2018 - ACS Publications
Microalgae are regarded as promising organisms to develop innovative concepts based on
their photosynthetic capacity that offers more sustainable production than heterotrophic …

[HTML][HTML] Towards a fully automated algorithm driven platform for biosystems design

M HamediRad, R Chao, S Weisberg, J Lian… - Nature …, 2019 - nature.com
Large-scale data acquisition and analysis are often required in the successful
implementation of the design, build, test, and learn (DBTL) cycle in biosystems design …

[HTML][HTML] Crops In Silico: Generating Virtual Crops Using an Integrative and Multi-scale Modeling Platform

A Marshall-Colon, SP Long, DK Allen, G Allen… - Frontiers in plant …, 2017 - frontiersin.org
Multi-scale models can facilitate whole plant simulations by linking gene networks, protein
synthesis, metabolic pathways, physiology, and growth. Whole plant models can be further …

SynBioHub: a standards-enabled design repository for synthetic biology

JA McLaughlin, CJ Myers, Z Zundel, G Mısırlı… - ACS synthetic …, 2018 - ACS Publications
The SynBioHub repository (https://synbiohub. org) is an open-source software project that
facilitates the sharing of information about engineered biological systems. SynBioHub …

[HTML][HTML] The synthetic biology open language (SBOL) version 3: simplified data exchange for bioengineering

JA McLaughlin, J Beal, G Mısırlı, R Grünberg… - … in Bioengineering and …, 2020 - frontiersin.org
The Synthetic Biology Open Language (SBOL) is a community-developed data standard that
allows knowledge about biological designs to be captured using a machine-tractable …

iBioSim 3: A Tool for Model-Based Genetic Circuit Design

L Watanabe, T Nguyen, M Zhang, Z Zundel… - ACS synthetic …, 2018 - ACS Publications
The iBioSim tool has been developed to facilitate the design of genetic circuits via a model-
based design strategy. This paper illustrates the new features incorporated into the tool for …

Design automation in synthetic biology

E Appleton, C Madsen, N Roehner… - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Design automation refers to a category of software tools for designing systems that work
together in a workflow for designing, building, testing, and analyzing systems with a target …

[HTML][HTML] Quantification of bacterial fluorescence using independent calibrants

J Beal, T Haddock-Angelli, G Baldwin, M Gershater… - PloS one, 2018 - journals.plos.org
Fluorescent reporters are commonly used to quantify activities or properties of both natural
and engineered cells. Fluorescence is still typically reported only in arbitrary or normalized …