Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics

N Singh, GR Sherin, G Mugesh - Angewandte Chemie, 2023 - Wiley Online Library
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …

Precision drug delivery to the central nervous system using engineered nanoparticles

J Gao, Z Xia, S Gunasekar, C Jiang, JM Karp… - Nature Reviews …, 2024 - nature.com
Abstract Development of novel therapies for central nervous system (CNS) disorders has
experienced a high failure rate in clinical trials owing to unsatisfactory efficacy and adverse …

Nanoceria, the versatile nanoparticles: Promising biomedical applications

MA Saifi, S Seal, C Godugu - Journal of Controlled Release, 2021 - Elsevier
Nanotechnology has been a boon for the biomedical field due to the freedom it provides for
tailoring of pharmacokinetic properties of different drug molecules. Nanomedicine is the …

Selenium-doped carbon quantum dots efficiently ameliorate secondary spinal cord injury via scavenging reactive oxygen species

W Luo, Y Wang, F Lin, Y Liu, R Gu, W Liu… - International journal of …, 2020 - Taylor & Francis
Background: The excess production of reactive oxygen species (ROS) after traumatic spinal
cord injury (TSCI) has been identified as a leading cause of secondary injury, which can …

Microglia-targeting nanotherapeutics for neurodegenerative diseases

N Zhao, NL Francis, HR Calvelli, PV Moghe - APL bioengineering, 2020 - pubs.aip.org
Advances in nanotechnology have enabled the design of nanotherapeutic platforms that
could address the challenges of targeted delivery of active therapeutic agents to the central …

[HTML][HTML] Nanostructured ceria: Biomolecular templates and (bio) applications

P Rozhin, M Melchionna, P Fornasiero, S Marchesan - Nanomaterials, 2021 - mdpi.com
Ceria (CeO2) nanostructures are well-known in catalysis for energy and environmental
preservation and remediation. Recently, they have also been gaining momentum for …

Physiological and pathological factors affecting drug delivery to the brain by nanoparticles

Y Islam, AG Leach, J Smith, S Pluchino… - Advanced …, 2021 - Wiley Online Library
The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is
known to be increasing due to an aging population and is anticipated to further grow in the …

Inflammatory microenvironment-targeted nanotherapies

G Zhang, L Ma, L Bai, M Li, T Guo, B Tian, Z He… - Journal of Controlled …, 2021 - Elsevier
Inflammatory microenvironments (IMEs) are common pathological characteristics and drive
the development of multiple chronic diseases. Thus, IME-targeted therapies exhibit potential …

Polymer nanotherapeutics: A promising approach toward microglial inhibition in neurodegenerative diseases

S Keshavarz Shahbaz, K Koushki… - Medicinal Research …, 2024 - Wiley Online Library
Nanoparticles (NPs) that target multiple transport mechanisms facilitate targeted delivery of
active therapeutic agents to the central nervous system (CNS) and improve therapeutic …