Materials design for bone-tissue engineering

GL Koons, M Diba, AG Mikos - Nature Reviews Materials, 2020 - nature.com
Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Layered double hydroxide nanostructures and nanocomposites for biomedical applications

L Yan, S Gonca, G Zhu, W Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
Layered double hydroxide (LDH) nanostructures and related nanocomposites have
attracted significant interest in biomedical applications including cancer therapy, bioimaging …

High-performance self-cascade pyrite nanozymes for apoptosis–ferroptosis synergistic tumor therapy

X Meng, D Li, L Chen, H He, Q Wang, C Hong, J He… - ACS …, 2021 - ACS Publications
As next-generation artificial enzymes, nanozymes have shown great promise for tumor
catalytic therapy. In particular, their peroxidase-like activity has been employed to catalyze …

Synthesis of CaCO3-based nanomedicine for enhanced sonodynamic therapy via amplification of tumor oxidative stress

Z Dong, L Feng, Y Hao, Q Li, M Chen, Z Yang, H Zhao… - Chem, 2020 - cell.com
Development of multifunctional stimuli-responsive nanomedicine is appealing for effective
cancer treatment. Herein, we utilize the biocompatible CaCO 3 nanoparticles as the …

Application of hydroxyapatite nanoparticles in tumor-associated bone segmental defect

K Zhang, Y Zhou, C Xiao, W Zhao, H Wu, J Tang… - Science …, 2019 - science.org
Hydroxyapatite (HA) has been widely applied in bone repair because of its superior
biocompatibility. Recently, a proliferation-suppressive effect of HA nanoparticles (n-HA) …

Ameliorating quercetin constraints in cancer therapy with pH-responsive agarose-polyvinylpyrrolidone-hydroxyapatite nanocomposite encapsulated in double …

A Samadi, M Pourmadadi, F Yazdian, H Rashedi… - International Journal of …, 2021 - Elsevier
Despite quercetin (QC) promising features for cancer therapy, low solubility, poor
permeability, and short biological half-life time significantly confine its application in cancer …

[HTML][HTML] 3D-printed tri-element-doped hydroxyapatite/polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone …

H Huang, L Qiang, M Fan, Y Liu, A Yang, D Chang… - Bioactive Materials, 2024 - Elsevier
The resection of malignant osteosarcoma often results in large segmental bone defects, and
the residual cells can facilitate recurrence. Consequently, the treatment of osteosarcoma is a …

Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications

C Qi, S Musetti, LH Fu, YJ Zhu, L Huang - Chemical Society Reviews, 2019 - pubs.rsc.org
Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …

Macrophage fusion event as one prerequisite for inorganic nanoparticle-induced antitumor response

S Chen, Z Xing, M Geng, R Zhao, X Yang, X Zhu… - Science …, 2023 - science.org
While most nanomaterials are designed to assist tumor therapy, some inorganic
nanoparticles have been reported to impede cancer development. We assume that the …

Biodegradable inorganic nanostructured biomaterials for drug delivery

AY Cai, YJ Zhu, C Qi - Advanced Materials Interfaces, 2020 - Wiley Online Library
Biodegradable inorganic drug nanocarriers are widely investigated for efficient drug delivery
with enhanced bioavailability and reduced side effects. An ideal drug nanocarrier should …