Serotonin (5-HT), a monoamine neurotransmitter synthesized in various populations of
brainstem neurons, plays an important role in modulating the activity of spinal networks …

Elaboration of appropriate responses to behavioral situations rests on the ability of selecting
appropriate motor outcomes in accordance to specific environmental inputs. To this end, the …

Ionotropic inputs to motoneurones have the capacity to depolarise and hyperpolarise the
motoneurone, whereas neuromodulatory inputs control the state of excitability of the …

Animal models indicate that motor behaviour is shaped by monoamine neuromodulators
released diffusely throughout the brain and spinal cord. As an alternative to conducting a …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects
selected cortical and spinal neuronal populations, leading to progressive paralysis and …

Vagus nerve stimulation (VNS) paired with rehabilitation training is emerging as a potential
treatment for improving recovery of motor function following stroke. In rats, VNS paired with …

Objective Spasticity occurs in a wide range of neurological diseases, including
neurodegenerative diseases, after trauma, and after stroke, and is characterized by …

Background Intracortical microstimulation (ICMS) is a technique used for a number of
purposes including the derivation of cortical movement representations (motor maps). Its …

Autism spectrum disorder (ASD) is an increasingly prevalent neurodevelopmental disorder
characterized by deficits in sociability and communication, and restricted and/or repetitive …

The behavioral modifications associated with early motherhood, which include high
aggression, caring for the young, and low anxiety, are all affected by acute pharmacological …