Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future

DM Good, V Thongboonkerd, J Novak… - Journal of proteome …, 2007 - ACS Publications
Sparked by the article from Lescuyer and colleagues in a recent issue, we aim here to
further encourage interest in and discussion of clinically relevant biomarker research. We …

Progress in understanding primary glomerular disease: insights from urinary proteomics and in-depth analyses of potential biomarkers based on bioinformatics

L Ge, J Liu, B Lin, X Qin - Critical Reviews in Clinical Laboratory …, 2023 - Taylor & Francis
Chronic kidney disease (CKD) has become a global public health challenge. While primary
glomerular disease (PGD) is one of the leading causes of CKD, the specific pathogenesis of …

Peptidome data-driven comprehensive individualized monitoring of membranous nephropathy with machine learning

Z Xu, R Chen, C Hao, Q Xie, C Deng, N Sun - Chinese Chemical Letters, 2024 - Elsevier
As the most common pathological type of nephrotic syndrome, membranous nephropathy
(MN) presents diversity in progression trends, facing severe complications. The precise …

Urinary proteomics: towards biomarker discovery, diagnostics and prognostics

V Thongboonkerd - Molecular bioSystems, 2008 - pubs.rsc.org
During recent years, the proteomics field has moved onward to clinical applications,
particularly for biomarker discovery, diagnostics and prognostics of human diseases. The …

Differential proteome profiling using iTRAQ in microalbuminuric and normoalbuminuric type 2 diabetic patients

J Jin, YH Ku, Y Kim, Y Kim, K Kim… - Journal of Diabetes …, 2012 - Wiley Online Library
Diabetic nephropathy (DN) is a long‐term complication of diabetes mellitus that leads to end‐
stage renal disease. Microalbuminuria is used for the early detection of diabetic renal …

[HTML][HTML] Urinary proteome of dogs with renal disease secondary to leishmaniosis

MA González, R Barrera-Chacón, FJ Peña… - Research in Veterinary …, 2022 - Elsevier
Canine leishmaniosis is frequently associated with the development of renal disease. Its
pathogenesis is complex and not fully understood. For this reason, this study aimed to …

Proteomics and glomerulonephritis: A complementary approach in renal pathology for the identification of chronic kidney disease related markers

V L'Imperio, A Smith, C Chinello… - PROTEOMICS …, 2016 - Wiley Online Library
Glomerulonephritis (GN) is one of the most common origins of chronic kidney disease and
its careful evaluation is crucial for prognostic and therapeutic purposes, with the renal biopsy …

Proteomic analysis of post-hemorrhagic shock mesenteric lymph

JF Fang, LY Shih, KC Yuan, KY Fang, TL Hwang… - Shock, 2010 - journals.lww.com
Recent studies have documented the association of mesenteric lymphatic route with adult
respiratory distress syndrome and multiple organ failure after hemorrhagic shock. However …

Urinary proteomics—a tool for biomarker discovery

M Pejcic, S Stojnev, V Stefanovic - Renal failure, 2010 - Taylor & Francis
The strong need for the discovery of novel disease markers together with the development of
high-throughput techniques that provide highly sensitive analysis of protein content in …

Two-dimensional difference gel electrophoresis urinary proteomic profile in the search of nonimmune chronic allograft dysfunction biomarkers

E Bañón-Maneus, F Diekmann, M Carrascal… - …, 2010 - journals.lww.com
Methods. Morning spot urine samples that were collected from kidney transplant recipients
with biopsy-proven interstitial fibrosis and tubular atrophy (IFTA) stages 0-I-II/III (n= 8/group) …