Selenium, aging and aging-related diseases

Z Cai, J Zhang, H Li - Aging clinical and experimental research, 2019 - Springer
Selenium is an essential trace element in the human body and plays an important role in the
body via selenoprotein, which contains selenium. Selenoproteins (glutathione peroxidase …

[HTML][HTML] Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases

I Abdulwaliyu, SO Arekemase, JA Adudu… - Clinical Nutrition …, 2019 - Elsevier
Background & aims Inadequate knowledge and intake of a balance diet is a contributing
factor of micronutrient deficiencies in developing countries. Phytic acid contributes in …

[HTML][HTML] Volumetric changes in the aging rat brain and its impact on cognitive and locomotor functions

HS Hamezah, LW Durani, NF Ibrahim… - Experimental …, 2017 - Elsevier
Impairments in cognitive and locomotor functions usually occur with advanced age, as do
changes in brain volume. This study was conducted to assess changes in brain volume …

[HTML][HTML] Antioxidative effects of ascorbic acid and astaxanthin on arpe-19 cells in an oxidative stress model

S Oh, YJ Kim, EK Lee, SW Park, HG Yu - Antioxidants, 2020 - mdpi.com
Oxidative stress has been implicated as critical pathogenic factors contributing to the
etiology of diabetic retinopathy and other retinal diseases. This study investigated …

Cross-sectional study: Relationship between serum trace elements and hypertension

Z Zhang, S Zhao, H Wu, W Qin, T Zhang… - Journal of Trace …, 2022 - Elsevier
Background A balanced intake of trace elements is beneficial for chronic diseases such as
hypertension. However, the available information regarding trace elements that may be …

[HTML][HTML] Anti-Diabetic Potential of Ocimum gratissimum Leaf Fractions in Fortified Diet-Fed Streptozotocin Treated Rat Model of Type-2 Diabetes

SIR Okoduwa, IA Umar, DB James, HM Inuwa - Medicines, 2017 - mdpi.com
Background: Ocimum gratissimum (OG) is used in the traditional management of diabetes in
Nigeria. This study investigated the anti-diabetic potential of OG leaf fractions (OGLF) in a rat …

[HTML][HTML] Biomarkers of lipid peroxidation related to hypertension in aging

H Yavuzer, S Yavuzer, M Cengiz, H Erman… - Hypertension …, 2016 - nature.com
The aim of this clinical study was to evaluate the influence of aging on the levels of lipid
peroxidation (quantified as thiobarbituric acid-reactive substances (TBARS) content), lipid …

The association of serum zinc and copper with hypertension: A meta-analysis

Z Li, W Wang, H Liu, S Li, D Zhang - Journal of Trace Elements in Medicine …, 2019 - Elsevier
Objective The association of serum zinc (Zn), copper (Cu) with the risk of hypertension (HT)
remains controversial. Therefore, we conducted a meta-analysis to explore the relationships …

[HTML][HTML] Lipotoxic impairment of mitochondrial function in β-cells: A review

A Römer, T Linn, SF Petry - Antioxidants, 2021 - mdpi.com
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial
dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through …

[HTML][HTML] Validation of the antidiabetic effects of Vernonia amygdalina delile leaf fractions in fortified diet-fed streptozotocin-treated rat model of type-2 diabetes

SIR Okoduwa, IA Umar, DB James… - Journal of …, 2017 - journals.lww.com
Background: Vernonia amygdalina (VA) is used in the traditional management of diabetes in
Nigeria. Previous scientific verification of VA is on Type-1 diabetes model, in spite of the …