More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

All positive strand RNA viruses are known to replicate their genomes in close association
with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family …

Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …

The availability of the first molecular clone of the hepatitis C virus (HCV) genome allowed
the identification and biochemical characterization of two viral enzymes that are targets for …

Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …

Exciting progress has recently been made in understanding the replication of hepatitis C
virus, a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma …

Great progress has been made over the past years in elucidating the structure and function
of the hepatitis C virus (HCV) proteins, most of which are now actively being pursued as …

Hepatitis C virus (HCV) is a global health problem, because infection frequently leads to
chronic hepatitis C eventually progressing to liver cirrhosis and liver cancer. Improved …

The nonstructural 5A (NS5A) protein is a target for drug development against hepatitis C
virus (HCV). Interestingly, the NS5A inhibitor daclatasvir (BMS-790052) caused a decrease …