Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …

Cervical cancer (CC) is one of most common malignancies affecting women worldwide. To
date, surgical resection is the only effective radical remedy for CC at its early stages, while …

Aurora B kinase (AURKB) inhibitors have been trialled in a range of different tumour types
but are not approved for any indication. Expression of the human papilloma virus (HPV) …

Purpose: Human papillomavirus (HPV) causes> 5% of cancers, but no therapies uniquely
target HPV-driven cancers. Experimental Design: We tested the cytotoxic effect of 864 drugs …

Background Cervical cancer as one of the most common malignant tumors lead to bad
prognosis among women. Some researches already focus on the carcinogenesis and …

The major HPV oncogenes, E6 and E7, are known for its notoriety in driving the
carcinogenic process in human papilloma virus (HPV) driven cancers. It is well-established …

To address the unmet need for effective biomarker-driven targeted therapy for human
papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) and …

Polyploidy is a common outcome of chemotherapies, but there is conflicting evidence as to
whether polyploidy is an adverse, benign or even favourable outcome. We show Aurora B …

The expression of human papillomavirus (HPV) oncoproteins perturbed multiple cellular
events of the host cells, leading to the formation of cancer phenotypes. Our current and …

Oncogenic signalling confers tumour-progression advantages; thus, its pharmacological
blockade is the best strategy for cancer chemotherapy. However, drug resistance and …