Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature

A Ishak, M Mehendale, MM AlRawashdeh… - Gene, 2022 - Elsevier
Background COVID-19 is associated with several risk factors such as distinct ethnicities
(genetic ancestry), races, sexes, age, pre-existing comorbidities, smoking, and genetics. The …

[HTML][HTML] Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

M Stravalaci, I Pagani, EM Paraboschi, M Pedotti… - Nature …, 2022 - nature.com
The humoral arm of innate immunity includes diverse molecules with antibody-like functions,
some of which serve as disease severity biomarkers in coronavirus disease 2019 (COVID …

[HTML][HTML] Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

C Dieter, LA Brondani, CB Leitão, F Gerchman… - PLoS …, 2022 - journals.plos.org
Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

[HTML][HTML] Potential genes associated with COVID-19 and comorbidity

S Feng, F Song, W Guo, J Tan, X Zhang… - … journal of medical …, 2022 - ncbi.nlm.nih.gov
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …

[HTML][HTML] Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups

L Hurler, Á Szilágyi, F Mescia, L Bergamaschi… - Frontiers in …, 2023 - frontiersin.org
Introduction While complement is a contributor to disease severity in severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, all three complement …

[HTML][HTML] Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know

WM Zelek, RA Harrison - Immunobiology, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

[HTML][HTML] Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies

MN Ahmed, R Jahan, V Nissapatorn… - Biomedicine & …, 2022 - Elsevier
Lectins or clusters of carbohydrate-binding proteins of non-immune origin are distributed
chiefly in the Plantae. Lectins have potent anti-infectivity properties for several RNA viruses …

[HTML][HTML] Genetic susceptibility to severe COVID-19

C Cappadona, V Rimoldi, EM Paraboschi… - Infection, Genetics and …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the
coronavirus disease 2019 (COVID-19) pandemic. Clinical manifestations of the disease …

[HTML][HTML] Complement-mediated microvascular injury and thrombosis in the pathogenesis of severe COVID-19: A review

P Gianni, M Goldin, S Ngu, S Zafeiropoulos… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) causes acute microvascular thrombosis in
both venous and arterial structures which is highly associated with increased mortality. The …