Hemophagocytic lymphohistiocytosis (HLH) is a syndrome describing patients with severe
systemic hyperinflammation. Characteristic features include unremitting fever, cytopenias …

X-linked inhibitor of apoptosis (XIAP) deficiency is a rare inborn error of immunity first
described in 2006. XIAP deficiency is characterised by immune dysregulation and a broad …

The development of human mesenchymal stromal/stem cell (MSC)-based therapy has
focused on exploring biological nanoparticles secreted from MSCs. There is emerging …

XIAP (X-linked inhibitor of apoptosis) deficiency is a rare inborn error of immunity. XIAP
deficiency causes hyperinflammatory disease manifestations due to dysregulated TNF …

Acute graft-versus-host disease (GVHD) is 1 of the major life-threating complications after
allogeneic cell transplantation. Although steroids remain first-line treatment, roughly one-half …

Despite advances in immunosuppressive prophylaxis and overall supportive care,
gastrointestinal (GI) graft-versus-host disease (GVHD) remains a major, lethal side effect …

Acute graft-versus-host disease (aGVHD) is the main complication of and cause of death
after allogeneic hematopoietic stem cell transplantation. Baicalin can protect the small …

Tissue-intrinsic mechanisms that regulate severity of systemic pathogenic immune-mediated
diseases, such as acute graft-versus-host disease (GVHD), remain poorly understood …

X-linked inhibitor of apoptosis (XIAP) deficiency is an inherited primary immunodeficiency
characterized by chronic inflammasome overactivity and associated with hemophagocytic …

Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare life-threatening
complication of blood transfusion caused by donor T cells that escape rejection by the …