[HTML][HTML] The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

[HTML][HTML] DNA nanostructure-based nucleic acid probes: construction and biological applications

DX Wang, J Wang, YX Wang, YC Du, Y Huang… - Chemical …, 2021 - pubs.rsc.org
In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …

New opportunities for immunomodulation of the tumour microenvironment using chemical tools

JY Su, WH Li, YM Li - Chemical Society Reviews, 2022 - pubs.rsc.org
Immunotherapy is recognised as an attractive method for the treatment of cancer, and
numerous treatment strategies have emerged over recent years. Investigations of the tumour …

Fluid nanoporous microinterface enables multiscale-enhanced affinity interaction for tumor-derived extracellular vesicle detection

Q Niu, J Gao, K Zhao, X Chen, X Lin… - Proceedings of the …, 2022 - National Acad Sciences
Tumor-derived extracellular vesicles (T-EVs) represent valuable markers for tumor diagnosis
and treatment guidance. However, nanoscale sizes and the low abundance of marker …

[HTML][HTML] A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy

T Cui, Y Zhang, G Qin, Y Wei, J Yang, Y Huang… - Nature …, 2023 - nature.com
Precise discrimination and eradication of cancer cells by immune cells independent of
antigen recognition is promising for solid tumor therapeutics, yet remains a tremendous …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

Cell surface-localized imaging and sensing

HR Jia, YX Zhu, QY Duan, FG Wu - Chemical Society Reviews, 2021 - pubs.rsc.org
Systematically dissecting the molecular basis of the cell surface as well as its related
biological activities is considered as one of the most cutting-edge fields in fundamental …

Cell-specific aptamers as potential drugs in therapeutic applications: A review of current progress

J Yuhan, L Zhu, L Zhu, K Huang, X He, W Xu - Journal of Controlled …, 2022 - Elsevier
Cell-specific aptamers are a promising emerging player in the field of disease therapy. This
paper reviews the multidimensional research progress made in terms of their classification …

Reassembly of Peptide Nanofibrils on Live Cell Surfaces Promotes Cell–Cell Interactions

P Guo, D Wang, S Zhang, D Cheng, S Wu, X Zuo… - Nano Letters, 2023 - ACS Publications
Nature regulates cellular interactions through the cell-surface molecules and plasma
membranes. Despite advances in cell-surface engineering with diverse ligands and reactive …