Cognitive impairments are now recognized as one of the most ubiquitous features of
schizophrenia. These impairments can be detected before the onset of symptoms that meet …

BACKGROUND: We reviewed previous studies comparing schizophrenia patients and
healthy subjects for performance on the Iowa Gambling Task (IGT)(a laboratory task …

BACKGROUND: Significant neuropsychological (NP) and functional deficits are found in
most schizophrenia patients. Previous studies have left questions as to whether global NP …

Neurocognition is moderately to severely impaired in patients with schizophrenia. However,
the factor structure of the various neurocognitive deficits, the relationship with symptoms and …

Objective: Patients with schizophrenia frequently present with negative symptoms and
cognitive impairments for which no effective treatments are known. Agents that act at the …

Although individuals with schizophrenia show a lifetime prevalence of 50% for suffering from
a comorbid substance use disorder, substance abuse usually represents an exclusion …

Although a substance use disorder (SUD) is traditionally associated with psycho–bio-social
impairments, recent investigations among persons with schizophrenia (Sz) generated …

Cognitive impairments in schizophrenia are well documented and correlated with functional
disability. Although some patients demonstrate normal neuropsychological (NP) functioning …

Alcohol use disorders (AUDs) represent a severe, world-wide problem, and are usually
comorbid with psychiatric disorders, comorbidity increases the risks associated with AUDs …

Addiction is a frequent comorbid disorder in schizophrenia related to dopaminergic
dysfunction in fronto-subcortical circuits. These brain networks are relevant for both …