Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …

Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …

Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …

Thermosensitive liposomes are a promising tool for external targeting of drugs to solid
tumors when used in combination with local hyperthermia or high intensity focused …

Introduction Tumor cells can effectively be killed by heat, eg by using magnetic
hyperthermia. The main challenge in the field, however, is the generation of therapeutic …

There is a rapidly increasing interest in developing stimuli‐responsive nanomaterials for
treating a variety of diseases. By enabling the activation of function locally at the sites of …

The past few decades have seen great progress in the exploration of nanoparticles (NPs) as
novel tools for cancer treatments and diagnosis. Practical and reliable application of …

Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for
over 40 years and remains one of the most used drugs in chemotherapy for a variety of …