[HTML][HTML] Extracellular vesicles in the pathogenesis and treatment of acute lung injury

Q Hu, S Zhang, Y Yang, JQ Yao, WF Tang… - Military Medical …, 2022 - Springer
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-
threatening lung diseases associated with acute and severe inflammation. Both have high …

[HTML][HTML] The role of neutrophil extracellular traps in acute lung injury

D Scozzi, F Liao, AS Krupnick, D Kreisel… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

[HTML][HTML] Citrullination in the pathology of inflammatory and autoimmune disorders: recent advances and future perspectives

O Ciesielski, M Biesiekierska, B Panthu… - Cellular and Molecular …, 2022 - Springer
Numerous post-translational modifications (PTMs) govern the collective metabolism of a cell
through altering the structure and functions of proteins. The action of the most prevalent …

[HTML][HTML] HMGB1-mediated neutrophil extracellular trap formation exacerbates intestinal ischemia/reperfusion-induced acute lung injury

YQ Zhan, YH Ling, Q Deng, YX Qiu… - The Journal of …, 2022 - journals.aai.org
Influx of activated neutrophils into the lungs is the histopathologic hallmark of acute lung
injury (ALI) after intestinal ischemia/reperfusion (I/R). Neutrophils can release DNA and …

The role of neutrophil extracellular traps in sepsis and sepsis-related acute lung injury

S Zou, H Jie, X Han, J Wang - International immunopharmacology, 2023 - Elsevier
Neutrophils release neutrophil extracellular traps (NETs) to trap pathogenic microorganisms.
NETs are involved in the inflammatory response and bacterial killing and clearance …

Role of neutrophil extracellular traps in inflammatory evolution in severe acute pancreatitis

H Kang, Y Yang, L Zhu, X Zhao, J Li, W Tang… - Chinese Medical …, 2022 - mednexus.org
Severe acute pancreatitis (SAP) is a life-threatening acute abdominal disease with two
peaks of death: the first in the early stage, characterized by systemic inflammatory response …

[HTML][HTML] Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

C Carmona-Rivera, Y Zhang, K Dobbs, TE Markowitz… - JCI insight, 2022 - ncbi.nlm.nih.gov
Dysregulation in neutrophil extracellular trap (NET) formation and degradation may play a
role in the pathogenesis and severity of COVID-19; however, its role in the pediatric …

Epigenetic regulation of pulmonary inflammation

S Ahmad, XL Zhang, A Ahmad - Seminars in cell & developmental biology, 2024 - Elsevier
Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

[HTML][HTML] Coinfections in the lung: How viral infection creates a favorable environment for bacterial and fungal infections

JJ Obar, KM Shepardson - Plos Pathogens, 2023 - journals.plos.org
While it is well established that secondary bacterial pneumonia plays a significant role in the
morbidity and mortality of patients with severe respiratory viral infections, bacteria are not the …

[HTML][HTML] Neutrophils drive pulmonary vascular leakage in MHV-1 infection of susceptible A/J mice

HH Gong, MJ Worley, KA Carver, DR Goldstein… - Frontiers in …, 2023 - frontiersin.org
Background Lung inflammation, neutrophil infiltration, and pulmonary vascular leakage are
pathological hallmarks of acute respiratory distress syndrome (ARDS) which can lethally …