Premotor, nonmotor and motor symptoms of Parkinson's disease: a new clinical state of the art
ABRL Silva, RWG de Oliveira, GP Diógenes… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is a neurodegenerative disorder that affects dopaminergic
neurons in the mesencephalic substantia nigra, causing a progressive clinical course …
neurons in the mesencephalic substantia nigra, causing a progressive clinical course …
[HTML][HTML] Circadian rhythms and astrocytes: the good, the bad, and the ugly
MH Hastings, M Brancaccio… - Annual review of …, 2023 - annualreviews.org
This review explores the interface between circadian timekeeping and the regulation of
brain function by astrocytes. Although astrocytes regulate neuronal activity across many time …
brain function by astrocytes. Although astrocytes regulate neuronal activity across many time …
[HTML][HTML] NADPH and mitochondrial quality control as targets for a circadian-based fasting and exercise therapy for the treatment of Parkinson's disease
WM Curtis, WA Seeds, MP Mattson, PC Bradshaw - Cells, 2022 - mdpi.com
Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …
Sleep and circadian rhythms in α‐synucleinopathies—perspectives for disease modification
D Kunz, H Oster, O Rawashdeh… - Acta …, 2023 - Wiley Online Library
The global north is facing an unprecedented rise in the prevalence of neurodegenerative
diseases. The increasing incidence of Parkinson's disease is being referred to as a …
diseases. The increasing incidence of Parkinson's disease is being referred to as a …
[HTML][HTML] Neurological insights into sleep disorders in Parkinson's disease
S Thangaleela, BS Sivamaruthi, P Kesika, S Mariappan… - Brain sciences, 2023 - mdpi.com
Parkinson's disease (PD) is a common multidimensional neurological disorder
characterized by motor and non-motor features and is more prevalent in the elderly. Sleep …
characterized by motor and non-motor features and is more prevalent in the elderly. Sleep …
Effect of aging and a dual orexin receptor antagonist on sleep architecture and non-REM oscillations including an REM behavior disorder phenotype in the PS19 …
The impact of tau pathology on sleep microarchitecture features, including slow oscillations,
spindles, and their coupling, has been understudied, despite the proposed importance of …
spindles, and their coupling, has been understudied, despite the proposed importance of …
[HTML][HTML] A mouse model of sleep disorders in Parkinson's disease showing distinct effects of dopamine D2-like receptor activation
D de Castro Medeiros, C Plewnia, RV Mendes… - Progress in …, 2023 - Elsevier
Excessive daytime sleepiness (EDS) and sleep fragmentation are often observed in
Parkinson's disease (PD) patients and are poorly understood despite their considerable …
Parkinson's disease (PD) patients and are poorly understood despite their considerable …
[HTML][HTML] Physical activity and sleep pattern in relation to incident Parkinson's disease: a cohort study
LH Chen, SY Sun, G Li, X Gao, W Luo, H Tian… - International Journal of …, 2024 - Springer
Background How physical activity (PA) and different sleep traits and overall sleep pattern
interact in the development of Parkinson's disease (PD) remain unknown. Objective To …
interact in the development of Parkinson's disease (PD) remain unknown. Objective To …
[HTML][HTML] Vitamin B12 ameliorates the pathological phenotypes of multiple Parkinson's disease models by alleviating oxidative stress
Y Wu, Z Zhao, N Yang, C Xin, Z Li, J Xu, B Ma, KL Lim… - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by progressive loss of dopaminergic neurons in the substantia nigra of the …
characterized by progressive loss of dopaminergic neurons in the substantia nigra of the …
Sleep and sleep disorders in people with Parkinson's disease
A Iranzo, VC De Cock, ML Fantini… - The Lancet …, 2024 - thelancet.com
Sleep disorders are common in people with Parkinson's disease. These disorders, which
increase in frequency throughout the course of the neurodegenerative disease and impair …
increase in frequency throughout the course of the neurodegenerative disease and impair …