While systemic lupus erythematosus (SLE) is an autoantibody and immune complex disease
by nature, most of its organ manifestations are in fact inflammatory. SLE activity scores thus …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Rheumatoid arthritis, juvenile idiopathic arthritis, the seronegative spondyloarthropathies
including psoriatic arthritis, and systemic lupus erythematosus are all examples of rheumatic …

Several autoimmune diseases are thought to be mediated in part by interleukin (IL)-18.
Many are those with associated increased interferon-γ (IFNγ) levels such as systemic lupus …

5 Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanaham TK, Zurawski G,
Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA. IL-33, an interleukin-1-like …

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease
characterized by biological and clinical heterogeneity. The interleukin (IL)-1 superfamily is a …

Background: Inflammatory reactions and other events in early life may be part of the etiology
of late-onset diseases, including cerebral palsy, autism, and type 1 diabetes. Most neonatal …

OBJECTIVES: To determine the circulating levels of Th1 and Th2 cytokines in patients with
systemic lupus erythematosus (SLE) and to elucidate their association with disease activity …

The pathogenesis of systemic lupus erythematosus (SLE) entails a complex interaction
between the different arms of the immune system. While autoantibodies production and …

Objective Macrophage activation syndrome (MAS) is a life-threatening complication of
systemic juvenile idiopathic arthritis (sJIA) characterised by a vicious cycle of immune …